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21st Century, Flea + Tick Defense for Dogs 23-44 lbs., 3 Applicators, 0.045 fl oz Each

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In Stock
  • Product Code: CEN-00051
  • UPC Code: 026664000514
  • Package Quantity: 3 Applicators, 0.045 fl oz Each
  • Dimensions: 5.8 x 0.7 x 4.8 in, 0.1 lbs (0.05 kg)
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Product Overview


Contains Fipronil the active ingredient used in Frontline® - Top Spot for Dogs*

  • Fast-Acting, Long-Lasting
  • Kills Fleas
  • Kills Ticks
  • Kills Chewing Lice
  • Waterproof

Kills Fleas, Ticks & Lice

Flea + Tick Defense for Dogs contains the active ingredient fipronil that effectively targets fleas, ticks, and chewing lice. Fipronil collects in the oils of the skin and hair follicles, and continues to be released from hair follicles onto the skin and coat, resulting in long-lasting activity.


  • Kills adult fleas before they lay eggs
  • Controls flea re-infestation for up to one month (4 weeks)
  • Controls fleas which may cause flea allergy dermatitis


  • Kills ticks that may transmit Lyme disease, Rocky Mountain spotted fever, ehrlichiosis, and babesiosis


  • Rapidly eliminates infestations with chewing lice


  • Aids in control of sarcoptic mange infestations

Suggested Use

For Dogs and Puppies - Use only on dogs weighing 23-44 lbs and 8 weeks or older

Other Ingredients

Active Ingredient %
Fipronil 9.7%
Other Ingredients 90.3%
Total 100.0%

Contains Fipronil the active ingredient used in Frontline Top Spot for Dogs

*Frontline® and Frontline Top Spot for Dogs® are registered trademarks of Merial.


Caution: Keep out of reach of children

See label insert for precautionary and first aid statements.

Do not use on cats. Keep cats away from treated dogs for 24 hours. If applied to a cat or ingested by a cat, contact your veterinarian.

iHerb Customer Reviews
5 Stars
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1 Stars

Just put first dose on dog not long enough time to really evaluate

Posted by 4809866925433511875 on May 03, 2016

1st month just put on dog two days ago so have not been able to evaluate as of yet. Gave two stars for packaging and convience.

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Didn't work for us

Posted by YoungerNextYear on Mar 02, 2016

I thought maybe this product would work and that I would be able to order from iHerb instead of making a special trip to the pet store but unfortunately, it isn't strong enough for our dog.

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not shipping to Hong Kong due to restrictions?

Posted by BomBom on Dec 07, 2015

It's a cheaper alternative of Frontline Plus which is almost twice as expensive. Very sad that iherb no longer ships this product to hong kong.

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Effective without issues

Posted by Reviewer1612446 on Mar 25, 2015

This flea product worked as well as the well known name brands and my dog didn't have any itching or adverse reactions from it. That's all I can ask.

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great product but I would like also to have a mosquito defense

Posted by 5068498325224671782 on Jul 25, 2014

It has good quality in low price but I think it is better for winter. During the summer I'm afraid my dog needs also protection from the mosquitos. It is a great product but I would like it also to have a mosquito defense

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