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Doctor's Best, 5-HTP, Enhanced with Vitamins B6 & C, 120 Veggie Caps

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In Stock
  • Expiration Date: Feb 2019
  • Shipping Weight: 0.3 lbs (0.14 kg)
  • Product Code: DRB-00120
  • UPC Code: 753950001206
  • Package Quantity: 120 Veggie Caps
  • Dimensions: 4.4 x 2.4 x 2.4 in, 0.25 lbs (0.11 kg)
Product Overview


  • Science-Based Nutrition
  • Dietary Supplement
  • Helps Maintain Mental and Emotional Well-Being
  • Suitable for vegetarians

5-HTP (5-hydroxy L-tryptophan) is a naturally occurring metabolite of the amino acid tryptophan. 5-HTP is converted in the brain to serotonin, a neurotransmitter substance found at the junctions (synapses) between neurons. 5-HTP helps maintain mental and emotional well-being and promotes healthy sleep. Doctor's Best 5-HTP is extracted from the seeds of the Griffonia simplicifolia plant.

Suggested Use

One capsule, one to three times daily, with or without food.

Other Ingredients

Modified cellulose (vegetarian capsule), rice powder, magnesium stearate (vegetable source), silicon dioxide.

Contains nothing other than listed ingredients.


Not to be used when taking MAO inhibitors, selective serotonin reuptake inhibitors (SSRIs), or other anti-depressant medications. It should also not used by individuals taking any of the category of medications known as "triptans".

Keep out of reach of children.

Best 5-HTP is tested to ensure that it does not contain "Peak X"

Supplement Facts
Serving Size: 1 capsule
Serving per container: 120 servings
  Amount Per Serving %Daily Value
Vitamin C 200 mg 333%
Vitamin B6 (as pyridoxine hydrochloride) 15 mg 750%
5-hydroxy L-tryptophan 100 mg
† Daily Value not established.
iHerb Customer Reviews

Calm again!

Posted by 5501389409676204844 on Jan 17, 2017

So, I have been using this supplement for about a week now. It works for me, but I needed to do some adjustments so I will be writing my experience with it. The first day i took it after dinner, and I felt a calming effect. The next day I took it with breakfast, and noticed a nauseating feeling about 1,5 hours after. The day after, I again took it in the morning, but skipped breakfast. Again, after 1-1,5 hours I got nauseous - and it made me sick so I had to leave work early. It made me throw up immediately when I came home. Sorry for the details, but this and reading some more about others experience made it clear to me that this dose (100mg) may not be necessary to everyone. Many get the same effect from 50 mg, 25 even. So I have started taking the supplement together with food, and only the content of half of the pill. I have experienced mild anxiety due to long term stress - which also has given me skin problems (rosacea). With this supplement the agitation is completeley (!) gone, I feel focused and experience less off the symptoms that comes with PMS. I think this is connected with hormonal imbalance, which often could be caused by stress (progesterone deficiency). So. What I've learned: - Take the supplement with food if you experience nausea - Begin with a lower dosage, you can always go higher if you get no effect - Use for 3 months, and then have a brake. (I have not found anything about long term use and side effects but this is affecting your brains production of seratonin, so I will take a pause from this when spring and the sunlight is back) - I have experienced no difference in my sleep, but then again I had no problems with it. But you need seratonin to make melatonin (and to sleep) so I can see how this may be helpful to those with sleep deprivation. - Even though I think it works as it should for me, I only give this product 4 out of 5 stars, because of the high dosage, and the size of the pill which may cause you to take waay too much and also makes it hard to swallow.

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Posted by 5657023369034802240 on Jan 16, 2017

My mood is much better and I have more initiative since starting to take 5-HTP.

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Posted by ivan94 on Dec 06, 2016

This product worked wonders for my mom. But in MY case.. all it did was make me feel way worse.

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Posted by 4759936352243265334 on Dec 05, 2016

Compared to 5-htp on its own it this is completely useless, treating depression and have completely relapsed since starting on this

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Traveler's alternative to Chia seeds

Posted by 5559196223017982901 on Dec 01, 2016

I take chia seeds in water every day but the routine is harder when traveling. The 5-HTP is a great alternative and my motivation level stays constant.

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