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Doctor's Best, SAM-e (S-Adenosyl-L-Methionine) 400, Double-Strength, 60 Enteric Coated Tablets

By Doctor's Best

MSRP:
$71.99
Our Price:
$35.15
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$36.84 (51)
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In Stock
  • Product Code: DRB-00252
  • UPC Code: 753950002524
  • Package Quantity: 60 Enteric Coated Tablets
  • Dimensions: 6.3 x 3.3 x 2 in, 0.25 lbs (0.11 kg)

Product Overview

Description
  • Science-Based Nutrition
  • Dietary Supplement with 400 mg Active S-Adenosyl Methionine Per Tablet
  • Enhances Mood & Neural Function
  • Promotes Joint Comfort & Mobility
  • Supports Liver Health & Detoxification
  • Pharmaceutical Grade
  • Sealed in Blister Packs for Freshness & Convenience
  • Suitable for Vegetarians

S-Adenosyl Methionine (SAMe) is derived from the amino acid methionine and is one of the most important methyl donors in the central nervous system. Methylation (donation of methyl groups) is an essential process in ensuring the proper function of a number of organ systems. SAMe is involved in numerous biochemical reactions in tissues including the liver, joints and brain. SAMe is also required for the biosynthesis of critical neurotransmitters and hormones.

Supplementing with SAMe

The manufacturing process of SAMe yields two forms, the S,S and the R,S isomers. The S,S isomer is the active form that mediates biochemical activity in the human body, whereas the R,S form is considered to be biologically inactive. The Italian SAMe used in Double-Strength SAMe 400 is processed to yield the highest available percentage of the active pure S,S form on the market.

SAMe and Joint Function

SAMe may enhance cartilage protection and promote the synthesis of proteoglycans, essential components of connective tissue. Clinical studies show an ability of SAMe to enhance mobility and movement, and promote joint comfort.

SAMe and Neural Health

SAMe-catalyzed methylation reactions promote the synthesis of neurotransmitters, which have the potential to promote enhanced mood. SAMe may also upregulate the production of phosphatidylcholine, supporting cognitive function.

SAMe and Liver Function

SAMe enhances liver synthesis of glutathione, an antioxidant. Glutathione promotes detoxification and liver production. Studies show SAMe may protect liver tissue from injury caused by a number of toxins.

Our Double-Strength SAMe 400 contains 400 mg of active SAMe in each tablet. Doctor's Best utilizes only the highest quality Italian SAMe available on the market. This ensures that you receive the most potent SAMe product with the highest percentage of the active S,S form per serving, bar none.

Double Strength SAMe is sealed in blister packs for freshness and stability.

Suggested Use

Adult Use: Take 1 tablet daily away from food, or as recommended by a nutritionally-informed physician. Do not chew or crush tablet.

Other Ingredients

Cellulose, methacrylic acid copolymer, glyceryl behenate, magnesium silicate, triethyl citrate, titanium dioxide, magnesium stearate, mannitol, glycerol palmitostearate, silicon dioxide, medium chain triglycerides, sodium carboxymethyl starch and iron oxide.

The SAMe found in Doctor's Best SAMe 400 mg (Double Strength) is free from yeast, dairy, gluten, soy, wheat and artificial flavoring

Contains nothing other than listed ingredients.

Warnings

Individuals using antidepressant medications should consult with their prescribing physician prior to using this product. Individuals diagnosed with bipolar disease or manic depression should avoid supplementing with SAMe. Do not use if pregnant or nursing. May cause gastrointestinal discomfort in a small percentage of people.

Store product in a cool, dry place to ensure maximum quality.

Visit Manufacturer's Website
Supplement Facts
Serving Size: 1 tablet
Servings Per Container: 60 servings
  Amount per serving % Daily Value
S-Adenosyl Methionine (from 800 mg SAM-e tosylate disulfate) 400 mg
† Daily Value not established.

iHerb Customer Reviews

5 Stars
4 Stars
3 Stars
(7)
2 Stars
(4)
1 Stars
(9)
 

great product

Posted by 5301095804449401452 on May 21, 2016

For those who don't methylate properly this product is great for people with allergies.

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A great product

Posted by 5239059776918062918 on May 18, 2016

Recommended by my doctor. I find it very helpful in keeping depression at bay.

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SAMe 400mg

Posted by 4884900099426473307 on May 03, 2016

I purchased this for my husband as our Doctor recommended SAMe to help him with his PTSD and Anxiety. He was without it for a couple of days and I found his mood changed whilst off the product. So it is working to some extent.

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Arthritus Pain

Posted by MartineTrinder on Apr 11, 2016

I started using this after reading a lot of personal experiences of using this in place of nurofen/panadol to relieve arthiritus joint pain.. WOW.. it really works.. REALLY WORK.. If i dont take it for a couple of days the horrible joint pain slowly starts to come back.. SAMe is amazing!

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good product

Posted by 5347185210272425520 on Feb 21, 2016

SAMe 400 helps me, to get my hormones in balance. That was a problem for me, and these capsuls helps me to get my goal.

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