Your Cart is Empty
But it doesn't have to be.
Continue Shopping.
Added to Cart
Cart Total:
Customers Also Bought:

Enzymatic Therapy, Petadolex, Pro-Active, 60 Softgels

Our Price:
You Save:
$19.07 (36)
Earn 10% Loyalty Credit ?

This product is already in your Wish List.

View Wish List

This product is now in your Wish List.

Sorry, this product is no longer in stock.

In Stock
  • Expiration Date: Feb 2019
  • Shipping Weight: 0.26 lbs (0.12 kg)
  • Product Code: EMT-04806
  • UPC Code: 763948048069
  • Package Quantity: 60 Softgels
  • Dimensions: 2.4 x 2.4 x 4.5 in, 0.15 lbs (0.07 kg)
Bundle Offer
Save $4.00 when you purchase these items today for only $40.87
Total: $44.87
Combo Discount: - $4.00
Together: $40.87

Sorry, this product is no longer in stock.

Product Overview


  • The Safe, Pure Butterbur
  • Relaxes Blood Vessels in the Head
  • Dietary Supplement

Enzymatic Therapy’s Petadolex Pro-Active supplement contains pure butterbur extract to support healthy blood vessel tone in the head, as well as normal blood flow in the brain.

The patented method of extraction for Petadolex Pro-Active ensures the valuable petasites compounds are captured, while leaving out toxic levels of inherent compounds such as pyrrolizidine alkaloids. This product is tested for pyrrolizidine alkaloids to guarantee safety, made possible by using this patented process (U.S. Patent #6,551,626).

For soothing comfort that improves with continued use, trust Petadolex Pro-Active for your entire family, as it is effective in both adults and children!

Petadolex Pro-Active supports healthy blood vessel relaxation in the brain. Blood vessel tone is influenced, in part, through neuralgic, vascular, and chemical factors.

Butterbur (Petasites hybridus) contains several compounds with bioactive properties. Two of these compounds, petasin and isopetasin support healthy blood vessel tone and circulation.

Petasin additionally provides nutritional support for cellular activity associated with the functioning of healthy blood vessel walls.

Suggested Use

Recommendations: One softgel three times daily for the first four weeks. Thereafter, one softgel twice daily.

Other Ingredients

Medium chain triglycerides, gelatin, vegetable glycerin, sorbitol, water, and riboflavin color.

Contains no sugar, salt, yeast, wheat, gluten, corn, soy, dairy products, artificial flavoring, or preservatives.


Caution: Do not use if pregnant or nursing. If taking prescription drugs, consult your healthcare practitioner prior to use.

Supplement Facts
Serving Size: 1 softgel
  Amount per softgel % DV
Purple Butterbur
(Petasites hybridus) (Petadolex brand) Root Extract standardized to contain 7.5 mg petasins and to be free of harmful levels of pyrrolizidine alkaloids (PAs)
50 mg **
**Daily Value not established.
iHerb Customer Reviews

too early

Posted by 5435419455865642911 on Jul 13, 2016

I've been taking these for less than a month and have now switched to "migraine prevention formula" which not only has butterburr but also other proven aid for migraine namely feverfew, magnesium and B12 i guess this is not an immediate solution but i am happy to keep with this for a few months if it will eventually help with the migraine - so many others seem to have received some good relief -

Verified Purchase

Was this review helpful to you?


Posted by 5236705603527293864 on Jan 07, 2015

It has been a long time coming

Verified Purchase

Was this review helpful to you?

Migraine headache (Throbbing)

Posted by 5718483447959303655 on Dec 04, 2013

It doesn't seem to work on me at all. My migraine is chronic and I get the throbbing headache from on a regularly basis. Initially, B2 works extremely well but it loses its effectiveness after 6 months.

Verified Purchase

Was this review helpful to you?

I guess I'm one of the few who can't take it

Posted by Reviewer2530443 on Mar 04, 2013

I have severe migraines, and my neurologist actually suggested I try butterbur, but she cautioned that one cannot take it if allergic to ragweed. Apparently I am allergic to something, because I had a bad reaction to this product; I developed a severe headache which lasted for the five days that I took the product, as well as breathing problems. Eventually, I realized it was most likely the Petadolex, I discontinued the product and felt better within a half a day. I'm really disappointed that it did not work for me.

Verified Purchase

Was this review helpful to you?

HIghly Recommended

Posted by 5292947439208493736 on Jan 05, 2013

I have now been taking this for 2 1/2 months and have been very pleased with it. I've tried just about every preventative treatment there is for my chronic migraines, including an exhaustive list of medications and botox. Thus far, I've found this to have been the most helpful treatment in reducing the frequency of my migraines. I also have noticed a significant decrease in the daily low grade headaches I've been experiencing.

Verified Purchase

Was this review helpful to you?