Jarrow Formulas, Natural SAM-e (S-Adenosyl-L-Methionine) 200, 200 mg, 60 Tablets
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- Full Potency
- In Foil Blister Pack
- S-Adenosyl Methionine
- 200 mg (Net Yield) SAM-e from 400 mg SAM-e Tosylate Disulfate
- Highest Concentration of Active S,S Form
- Enteric-Coated Tablets
- Net Yield
- Dietary Supplement
- Suitable for Vegetarians/Vegans
- Joint Strength
- Liver Detoxification
- Mood and Brain Function
Jarrow Formulas SAM-e 200 provides a full 200 mg SAM-e (net yield) from 400 mg of SAM-e tosylate disulfate. SAM-e 200 is manufactured under low temperature and low humidity and is enteric-coated to ensure a biologically active product.
Contains More of the Active S,S Form
Found in all living cells, SAM-e is a metabolite of methionine (an essential amino acid). SAM-e is a chiral molecule and consists of two forms: (S,S) SAM-e and (R,S) SAM-e. The biologically active form is the (S,S) structure, while the (R,S) structure is biologically inactive. Jarrow Formulas SAM-e is made naturally by microbiological fermentation and then specially processed without solvents to preserve 68-80% (S,S) SAM-e, the highest active level available.
SAM-e has been clinically shown to have the following benefits:
SAM-e supports the production of healthy connective tissue through transulfuration. In this process, critical components of connective tissue, including glucosamine and the chondroitin sulfates, are sulfated by SAM-e metabolites.
SAM-e methylation reactions are involved in the synthesis of neurotransmitters such as L-DOPA, dopamine and related hormones, serotonin, epinephrine and phosphatidylcholine (a component of lecithin).
SAM-e metabolism supports the synthesis of glutathione (GSH) and glutathione-dependent enzymes (glutathione peroxidase and glutathione-S-transferase), which are substances important for liver function, including phase II detoxification.
Full Potency 200 mg SAM-e is derived from 400 mg of SAM-e tosylate disulfate.
Take 1 tablet 1 or 2 times per day on an empty stomach or as directed by your qualified healthcare professional.
For best result, use with Jarrow Formulas JarroSil, the biologically Activated Silicon.
Cellulose, mannitol, glycerol behenate, magnesium stearate (vegetable source), silicon dioxide, sodium starch glycolate, enteric coating (methacrylate copolymers), magnesium silicate, titanium dioxide, triethyl citrate, silicon dioxide and riboflavin.
No wheat, no gluten, no soybeans, no dairy, no egg, no fish/shellfish, no peanuts/tree nuts
Individuals using prescribed medications such as antidepressants, including Selective Serotonin Re-Uptake Inhibitors (SSRIs) and MAO Inhibitors should consult a physician before using. Individuals with Parkinson’s disease, bi-polar disorder or manic depression should not use SAM-e. Do not use if pregnant or nursing. Do not exceed recommended intake. May cause gastrointestinal upset in some persons. If you experience discomfort, discontinue use.
Jarrow Formulas Sam-e 200 is foil blister-packed to maximize stability and safety. Do not use if outer seal or blister pack is broken.
Store in a cool, dry place.
Keep out of the reach of children.
|Serving Size: 1 Tablet|
|Servings Per Container: 60|
|Amount Per Serving||% DV|
|S-Adenosyl Methionine (from 400 mg of SAM-e tosylate disulfate)||200 mg||*|
|* Daily Value not established.|
While I know that SAMe is wonderful...I took one of these and aprox. 5 hours later I was having horrific heart palpitations,dizziness,anxiety, pounding heart rate and panic attacks. The effects lasted several days. I was told by someone very knowledgable that this could mean that I may be very deficient of SAMe, which would explain my reaction. I just don't know if I could go through that again! He suggested to titrate slowly. I know I am an over methylator, this added to the intense reaction. Just be very careful. If you are sensitive go very low doses to begin with. I should have tried 25mg to start. It doesn't say potent for nothing! I love Jarrow products. I am still giving this 5 stars. My reaction by no means speaks poorly about the product itself.
I'm taking Jarrow Formulas, SAM-e 200 for the last 3 years and it is contunuing do deliver on tbe promise to help enhance my mood. The quality of this product is excellent, I can feel the difference.
If I could only take one supplement, this would be it.
Posted by 4612618648859402105 on Jul 10, 2016
I have been taking this product for four months. It has eased my headaches, improved my very low blood pressure, and improved my mood dramatically.
Good product, wasn't for us
Posted by 4612120995713906551 on May 05, 2016
This is a very well made product. My partner and I used the SAMe for a MTHFR protocol, and we got no results from it unfortunately. However, I know people who have used this for depression and undermethylation problems with great success. I personally responded very well to DLPA (for low endorphin levels) and my partner to GABA (for stress, inability to relax) so it appears we weren't lacking in SAMe or serotonin in the first place.
Posted by 4826387242143050930 on Feb 14, 2015
Love the product; I have been using Jarrow Sam-E for about 2 years. Found that it works best for me. Will not be ordering form iHerb again.They jump the price of the product just as I was checking out.Poor customer service.
Powerful Liver detoxifier
Posted by 5164720073768635172 on Jul 17, 2014
I may have to take a break with this because since I have been taking it I have really sore shoulders and other aches and pains. The only thing I can think of that would cause that is that it is detoxifying my liver too quickly. I may just take Milk Thistle for awhile and then try this again. I have been told before by a Naturopath that my liver function was poor, so I'm sure it's a great product and many seem to have good results, but may not be the right time for me to take it. I'll take a bit of a break and see how I feel and try and strengthen my liver first.
Works wonders for joint pain and mood! (with no side effects)
Posted by 5680244445204684826 on Jun 03, 2014
I started taking SAM-e (Jarrow brand) years ago for my liver (Hep C) and joints (runner's knee). I found out by coincidence that it is also WONDERFUL for depression as well, without any of the side effects you read about with anti-depressants. Also, it acts quickly - just a day or two to feel my mood lift. I stopped taking it for several years when it felt like my body had stabilized. Recently, I spiraled down into a deep dark place (due to several major life crises that hit in rapid succession), and found it difficult to solidly bounce back after several months until I remembered SAM-e and started taking it again - 400 mg/day. I felt better by the second day! I now take just 200 mg/day to maintain my mood & keep joint pain at bay. For now if I stop taking SAM-e, I feel my lower back injury as soon as I wake up the next day. Luckily, just 200 mg/day stops the pain within hours!