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- Pharmaceutical Grade, Stabilized
- Full Potency
- S-Adenosyl Methionine
- 400 mg (Net Yield) SAM-e from 800 mg SAM-e Tosylate Disulfate
- Highest Concentration of Active S, S Form
- 30 Count
- In Foil Blister Pack
- Gluten Free
- Dietary Supplement
- Joint Strength
- Liver Detoxification
- Mood and Brain Function
Jarrow Formulas SAM-e 400 provides a full 400 mg SAM-e (net yield) from 800 mg of SAM-e tosylate disulfate. SAM-e 400 is manufactured under low temperature and low humidity and is enteric-coated to ensure a biologically active product.
Contains More of the Active S,S Form
Found in all living cells, SAM-e is a metabolite of methionine (an essential amino acid). SAM-e is a chiral molecule and consists of two forms: (S,S) SAM-e and (R,S) SAM-e. The biologically active form is the (S,S) structure, while the (R,S) structure is biologically inactive. Jarrow Formulas SAM-e is made naturally by microbiological fermentation and then specially processed without solvents to preserve 68-80% (S,S) SAM-e, the highest active level available.
SAM-e has been clinically shown to have the following benefits:
SAM-e supports the production of healthy connective tissues through transulfuration. In this process, critical components of connective tissue, including glucosamine and the chondroitin sulfates, are sulfated by SAM-e metabolites.
SAM-e methylation reactions are involved in the synthesis of neurotransmitters such as L-DOPA, dopamine and related hormones, serotonin, epinephrine and phosphatidylcholine (a component of lecithin).
Methylation of DNA appears to be important in the suppression of errors in DNA replication. Demethylation of DNA is considered a contributor to the aging process. Proper methylation through substances such as SAM-e positively influences longevity.
SAM-e metabolism supports the synthesis of glutathione (GSH) and glutathione - dependent enzymes (glutathione peroxidase and glutathione - S- transferase), which are substances important for liver function.
Take 1 tablet per day on an empty stomach, or as directed by your qualified health care consultant.
For best result, use with Jarrow Formulas JarroSil, the biologically Activated Silicon.
Cellulose, mannitol, glyceryl behenate, magnesium stearate (vegetable source), silicon dioxide, sodium starch, glycolate, enteric coating (methacrylate copolymers), magnesium silicate, titanium dioxide, triethyl citrate, and riboflavin.
Suitable for vegetarians/vegans
No wheat, no gluten, no soybeans, no dairy, no egg, no fish/shellfish, no peanuts/tree nuts
Full Potency 400 mg SAM-e is derived from 800 mg of SAM-e tosylate disulfate.
Individual using prescribed medications such as antidepressants, including Selective Serotonin Re-Uptake Inhibitors (SSRI) and MAO Inhibitors should consult a physician before using. Individuals with Parkinson's disease, bi-polar disorder or manic depression should not use SAM-e.
This product complies with the proposed USP Monograph for SAM-e.
Jarrow Formulas Sam-e 400 is foil blister-packed to maximize stability and safety. Do not use if outer seal of blister pack is broken.
Store in a cool, dry place.
Keep out of the reach of children.
|Serving Size: 1 Tablet|
|Servings Per Container: 30|
|Amount Per Tablet||%DV|
|S-Adenosyl Methionine (from 800 mg of SAM-e tosylate disulfate)||400 mg||*|
|* Daily Value not established.|
This product has enabled me to relax and renew myself after the loss of my husband to cancer. It has allowed me to feel that I can sleep more easily and cope with the stresses that go along with living alone again.
I have been using the Jarrow SAM-e for the past 3 years and I've noticed a significant difference overall. My energy level has increased. I no longer have bouts of depression. My appetite has decreased which has helped me to control my weight.
I use this with DIM and Calcium-D-Glucarate
Posted by 5427527471212165275 on Dec 01, 2016
I use this to ensure estrogen detox. I have good experience with combining this with DIM and Calcium-D-Glucarate. Read my DIM review.
Posted by 4854800505304047973 on Nov 21, 2016
I suffer from chronic depression and this thing is effective for it just like a medicine. I think it is marketed as a medicine in certain countries. Really good.
Posted by 4616874238474659422 on Aug 01, 2016
Highly recommend for anyone. Helped with my deficiencies, moods and energy. Love this product!
Posted by 5563996035167001097 on Oct 21, 2015
I started taking SAM-e as i had read it helps with depression. Not only has it helped, i sleep better at night :)
Posted by 4766872620965520922 on Jun 09, 2015
I have used prescription antidepressants for years and have chosen to stop taking them. After a few months I became quite 'blue', easily upset and intraverted. I have found this product to help a great deal. I take one in the morning and in the afternoon I take one of Doctor's Best Best D-Phenylalanine 500mg tablets. I am way less tearfull and in a much better mood from day to day. I feel much more like my old self. Thank you iherb for a brilliant variety of excellent products as well as excellent delivery to New Zealand.