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- Pharmaceutical Grade, Stabilized
- Full Potency
- S-Adenosyl Methionine + Glucosamine
- 200 mg SAM-e (net yield)
- 525 mg Glucosamine HCl
- Highest Concentration of Active S,S Form
- 60 Enteric-Coated Tablets in Foil Blister Pack
- Dietary Supplement
- Joint strength
- Liver detoxification
- Mood and brain function
This product complies with the proposed USP Monograph for SAM-e.
Jarrow Formulas pharmaceutical grade, stabilized SAM-e Joint provides a full 200 mg SAM-e (net yield) and 525 mg of glucosamine hydrochloride in every enteric coated tablet. SAM-e Joint is manufactured under low temperature and low humidity and is enteric-coated to ensure a biologically active product. SAM-e and glucosamine are known to benefit joint function and recuperation.
Contains More of the Active S,S Form
Found in all living cells, SAM-e is a metabolite of methionine (an essential amino acid). SAM-e is a chiral molecule and consists of two forms: (S,S) SAM-e and (R,S) SAM-e. The biologically active form is the (S,S) structure, while the (R,S) structure is biologically inactive. Jarrow Formula's SAM-e is made naturally by microbiological fermentation and then specially processed without solvents to preserve 68-80% (S,S) SAM-e, the highest active level available.
Glucosamine is an aminosaccharide synthesized by transaminase enzymes from glucose and an amine group from glutamine. HCl (hydrochloric acid) stabilizes the glucosamine in this product. Glucosamine is a component of joint and intestinal tissue and is involved in the production of synovial fluid which lubricates the joints.
SAM-e has been clinically shown to have the following benefits:
SAM-e supports the production of healthy connective tissue through transulfuration. In this process, critical components of connective tissue, including glucosamine and the chondroitin sulfates, are sulfated by SAM-e metabolites.
SAM-e methylation reactions are involved in the synthesis of neurotransmitters such as L-DOPA, dopamine and related hormones, epinephrine and phosphatidylcholine (a component of lecithin).
Methylation of DNA appears to be important in the suppression of errors in DNA replication. Demethylation of DNA is considered a contributor to the aging process. Proper methylation through substances such as SAM-e positively influences longevity.
SAM-e metabolism supports the synthesis of glutathione (GSH) and glutathione-dependent enzymes (glutathione peroxidase and glutathione-S-transferase), which are substances important for liver function.
Full potency 200 mg SAM-e is derived from 400 mg of SAM-e tosylate disulfate.
Jarrow Formulas SAM-e Joint is Joint Sustain nutrition, providing glucosamine HCl, a sodium free form of glucosamine.
Take 1 to 2 tablets per day on an empty stomach, or as directed by your qualified health care consultant.
For best results, use with Jarrow Formulas JarroSil, the biologically Activated Silicon.
Cellulose, enteric coating (methacrylate copolymers), glyceryl behenate, silicon dioxide, talc, magnesium silicate, triethyl citrate, glyceryl palmitostearate, medium chain triglycerides, magnesium stearate (vegetable source), titanium dioxide, sorbitan oleate, yellow ochre and red iron oxide.
Contains: Shellfish (crab).
No wheat, no gluten, no soybeans, no dairy, no egg, no fish, no peanuts/tree nuts.
Do not use if allergic to shellfish. Individuals using prescribed medications such as antidepressants, including Selective Serotonin Re-Uptake Inhibitors (SSRIs) and MAO Inhibitors should consult a physician before using. Individuals with Parkinson's disease, bi-polar disorder or manic depression should not use SAM-e.
Jarrow Formulas Sam-e Joint is foil blister-packed to maximize stability and safety. Do not use if seal of blister pack is broken.
Store in a cool, dry place.
Keep out of the reach of children.
|Serving Size 1 Tablet|
|Serving Per Container: 60|
|Amount Per Tablet||% DV|
|S-Adenosyl Methionine (from 400 mg of SAM-e tosylate disulfate)||200 mg||*|
|Glucosamine HCl||525 mg||*|
|* Daily Value not established.|
I have been taking SAM-e (200 mg) every morning on an empty stomach for years. It is VERY effective in keeping away depression. I found it also helps with joint pain - used in conjunction with hylauronic acid. With these 2 supplements I am able to bend for long periods of time and get up with out pain. Last month I ran out of SAM-e and didn't may much attention to it. A couple of days after stopping SAM-e I noticed a BIG difference in my mood. I became depressed easily. It was as if black clouds hovered over me. I started back on the SAM-e and the black clounds passed.
Years ago, when I was probably about 74 I could not get right out of bed without taking a while to straighten up and it always hurt. I started taking Jarrow SAM-e, only 200mg, and I don't know when it happened but all of a sudden I realized I didn't have that stiffness anymore in the morning. So I just recently started taking it again, I am not going on 83, and it continues to help the arthritis in my neck and back and hips. I swear by it, great stuff, try it you will like it.
Posted by 5309943610220098292 on Jul 26, 2013
This product has given me releave from a knee injury that , in my case, is inoperable. It was recommended to me by my therapist and thanks to her, I feel better, overall.
Posted by run4bear on Jul 01, 2012
I do not feel that this product helped me.
Posted by Reviewer1804919 on Mar 21, 2012
I have been using this product for three weeks, I can already see the change I feel. Much more balanced and focused. Great product!
Jarrow Formulas Natural SAM-e
Posted by Reviewer2044696 on Aug 22, 2011
My mother takes this product as part of her arthritis treatment, and it helps in controlling the painful effects of arthritis. It is good and it is very effective.