- Pharmaceutical Grade, Stabilized
- Full Potency
- 200 mg Elemental SAM-e from 400 mg SAM-e Tosylate Disulfate
- Highest Concentration of Active S,S Form
- Longevity
- Joint Strength
- Liver Detoxification
- Mood & Brain Function
- In Foil Blister Pack
- Dietary Supplement
Jarrow FORMULAS® SAM-e 200 pharmaceutical grade, stabilized SAM-e is a full 200 mg elemental SAM-e from 400 mg of SAM-e tosylate disulfate. SAM-e 200 is manufactured under low temperature and low humidity and is enteric-coated to ensure a biologically active product.
Contains More of the Active S,S Form
SAM-e (S-Adenosylmethionine) is a chiral molecule and therefore consists of two forms: (S,S) SAM-e and (R,S) SAM-e. The biologically active form is the (S,S) structure, while the (R,S) structure is biologically inactive.
Jarrow FORMULAS SAM-e is made naturally by microbiological fermentation and then specially processed without solvents to preserve 68-80% (S,S) SAM-e the highest active level available.
SAM-e is an amino acid derivative that has been clinically proven to benefit brain, joint and liver function. Found in all living cells, SAM-e is also called "activated" methionine (an essential amino acid) since it is formed by the combining of ATP with methionine. SAM-e has undergone dozens of trials involving thousands of patients. Researchers studying the beneficial effects of SAM-e have identified the following benefits of SAM-e:
Joint Strength SAM-e supports the production of healthy connective tissue through transulfuration. In this process, critical components of connective tissue, including glucosamine and the chondroiton sulfates, are sulfated by SAM-e metabolites.
Brain Metabolism SAM-e methylation reactions are involved in the synthesis of neurotransmitters such as L-dopa, dopamine and related hormones, epinephrine and phosphatidylcholine (a component of lecithin).
Longevity Methylation of DNA appears to be important in the suppression of errors in DNA replication. Demethylation of DNA is considered a contributor to the aging process. Proper methylation through substances such as SAM-e positively influences longevity.
Liver SAM-e metabolism supports the synthesis of glutathione (GSH) and glutathionine-dependent enzymes (glutathionine peroxidase and glutathione-S-transferase), which are substances important for liver function.