7
of
7
people found the following review helpful
a smart antidepressant nutritional core,
April 10, 2009
From Virginia
TMG is a godsend. When I went off antidepressants rather suddenly and was fishing around for something to stop panic attacks and intense bad moods, TMG was the first consistent improvement. Four years later, it is still an indispensable part of my regimen. Perhaps its most important effect is recycling homocysteine into SAMe, which has antidepressant effects. Unchecked homocysteine sensitizes neurons to glutamate toxicity, and probably harms new neurons trying to grow in the hippocampus. Other B-vitamins have also helped me, especially B-2 and B-6 (pyridoxamine), along with fish oil and a non-choline source of uridine (for example magnesium orotate, or triacetyluridine). Some of these will help migraines and focus along with mood. I take 500 to 1000 mg TMG a day; much more may raise cholesterol. Don't mix with acetyl-l-carnitine (and in fact, if you're depressive, I'd advise against acetyl-l-carnitine altogether, thanks to its acetylcholinergic activity). TMG raises carnitine levels itself, and has a mild choline sparing effect. SAMe, by the way, is similar but not so safe; the surge in SAMe levels will create a surge in homocysteine. I tried combining the two, hoping TMG would recycle the homocysteine back SAMe, but I've found TMG on its own most stabilizing and effective.
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4
of
4
people found the following review helpful
It's WOW all over again,
January 17, 2007
By
Frederick Davis
from Utah
My first 48 hours with TMG have been real eye-openers. This is doing more of what methylb12 and SAM-E in the sense of a literal visual brightening, mood brightening, and a certain kind of energy increase, both did previously. On a very preliminary survey of the usual 5, it's a very positive response so far of 3 of 3 who have tried it. While the magitude of increase is below that of my initial methylb12 doses, it is larger than that of the SAM-e. This is the first brand I've tried so I have no idea if there are brand differences as with some products.
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claims from this review.
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3
of
3
people found the following review helpful
Very good product,
May 14, 2008
From New Jersey
Definitely helps if you have high homocysteine levels. My blurred vision improved.
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claims from this review.
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3
of
3
people found the following review helpful
Very effective!,
January 17, 2009
From Taiwan
Besides Methyl-B12 and SAM-e, this is the next best thing for helping me function as a normal person.
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2
of
2
people found the following review helpful
Jarrow quality,
March 12, 2009
By
David Pier
from North Carolina
The tablets don't bloat up from atmospheric moisture like the NOW tablets do.
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claims from this review.
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2
of
2
people found the following review helpful
TMG 500 mg,
November 23, 2008
From California
I appreciate getting supplements suitable for vegans. This product provides that.
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claims from this review.
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2
of
2
people found the following review helpful
Best I have tried,
May 16, 2008
By
Sam Morrison
from New Jersey
I have tried a three other brands and this is absolutely the most potent and effective. Very important for the choline system. Also Like that the tablets do not absorb moisture from the atmosphere and get puffy and crumbly like some of the other brands.
Update: 5/08 the tablets are no longer coated and now become puffy and crumble when exposed to air. Too bad because I loved this brand.
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1
of
1
people found the following review helpful
Great Value!!,
November 21, 2008
By
Robert Eenkema
from Tennessee
Two-a-day has kept my homocysteine in check.
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claims from this review.
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1
of
1
people found the following review helpful
liver support,
July 18, 2009
From Australia
Taking this helps your liver flush through undesirable estrogens.
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claims from this review.
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1
of
1
people found the following review helpful
Fantastic,
September 18, 2009
By
Rachel Dutton
from Armed Forces Pacific
This, along with L-Methionine (to make Sam-e), has really changed my life. I wouldn't have said I was depressed before, but now I am so much more optimistic and cheerful. My husband is on the same regimen (we each take one of each in the morning) and has has the same change. We ran out for a couple of days last week and both noticed a pretty dramatic difference. I won't be without this one again, and I honestly think everyone should try it.
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claims from this review.
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1
of
1
people found the following review helpful
Excellent,
September 21, 2009
From California
I feel more energetic, rested, and clear headed when I take this.
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claims from this review.
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1
of
1
people found the following review helpful
Great for Reducing Homosysteine,
April 15, 2008
From California
These keep my homosysteine numbers very low.
Note: iHerb does not imply any medical
claims from this review.
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