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Life Extension, Se-Methyl L-Selenocysteine, 200 mcg, 100 Veggie Caps (Discontinued Item)

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Out of Stock - Discontinued
  • Shipping Weight: 0.18 lbs (0.08 kg)
  • Product Code: LEX-16791
  • UPC Code: 737870167914
  • Package Quantity: 100 Veggie Caps
  • Dimensions: 2.1 x 2.1 x 3.9 in, 0.15 lbs (0.07 kg)
Product Overview


  • Foundation for Longer Life
  • Advanced Form of Selenium
  • Dietary Supplement

Se-Methyl L-Selenocysteine (SeMC) is a naturally occurring seleno-amino acid that is synthesized by plants such as garlic and broccoli. SeMC is an organoselenium compound and also more bioabsorbable that other forms. Unlike selenomethionine, which is incorporated into proteins in place of methionine, SeMC is not incorporated into any proteins...so it is fully available for the synthesis of selenium-containing enzymes, such as glutathione peroxidase.

Suggested Use

Read the entire label and follow the directions carefully prior to use.

Take one (1) capsule per day with a meal, or as recommended by a healthcare practitioner.

Other Ingredients

Rice flour, vegetable cellulose (capsule), ascorbyl palmitate.


  • Keep out of reach of children.
  • Do not exceed recommended dose.
  • Do not purchase if outer seal is broken or damaged.
  • When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.

Store tightly closed in a cool, dry place.

To report a serious adverse event or obtain product information, contact 1-866-280-2852.

Supplement Facts
Serving Size: 1 Vegetarian Capsule
  Amount Per Serving % Daily Value
Selenium (as Se-Methyl L-Selenocysteine) 200 mcg 286%
iHerb Customer Reviews
No better than selenomethionine
Why I became interested in selenium - it regulates 5-lipoxygenase (which converts EFAs into leukotrienes) and circadian rhythm. However, this one caused my hips to seize up (which I suppose could mean it's really effective and therefore antagonising something else? e.g. vit D, sulfur, chromium). Note re breast cancer research - one of the major studies actually showed selenium *increased* risk when supplemented by itself, which makes sense if you consider that *low* doses of selenium are synergistic with vit D. If vit D is low, more selenium may lower vit D further, and low vit D is also correlated with increased risk of breast cancer. High doses of selenium also antagonise other minerals such as magnesium, zinc, chromium - all required for reducing disease/inflammation and ensuring bone/endocrine health. Anyway - after trying four different brands/types of selenium - this one, selenomethionine, sodium selenite, sodium selenate - I kind of wonder if more benefit is derived from the sulfur rather than the selenium - though everyone is different, yes? Consider that sulfur and selenium are synergists - more selenium needs more sulfur (and vice versa). Foods such as rice/nuts/seeds are low in/antagonise sulfur via nutrients they contain (e.g. B15). Also - the fillers in this are weirdly non-hypoallergenic - Rice flour? Palmitate? Why? Essentially I won't buy again - if I feel I need extra selenium, I'll take selenomethionine - it never causes my hips to seize up and I can easily cut the tabs in half if I want to take fifty micrograms. Two hundred micrograms is way too much. Megadosing is foolish IMHO. If this review was helpful to you, please click YES below - thank you. For reviews of all the products I have purchased from iHerb, please click my username above.
Mar 21, 2014

Doctor recommended

Posted by 5001938772550186778 on Sep 03, 2016

Said that it is the best selenium dietary supplement

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Life Extension = Worth it

Posted by 5589595600852730495 on May 10, 2016

Don't want cancer? Selenium.

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the most bioavailable form of selenium

Posted by KentuckyWildcat on Dec 30, 2014

I have taken this product for many years. I have tried other forms of selenium but respond best to this one. I recently started taking iodine and was breaking out with acne, so I increased my dosage of selenium from 200 mcg to 400 mcg per day. The acne was gone within two days and has not reappeared even though I have increased my intake of iodine. Selenium is used in the body's manufacture of glutathione, a potent antioxidant.

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Posted by Reviewer1829477 on May 15, 2014

I have taken selenium yeast supplements just fine. I read that this was supposed to be the best form and most bio-available. I GET INSTANTLY SICK WHEN I TAKE IT. I tried three times and it ruined 3 days of my life. ---I love Iherb.com so much but I am really bummed that there is no return option for situations like this. I even emailed about it but I only got a canned response, a bit disappointing.

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This is supossed to be the best form of selenium to use.

Posted by 4782523585447708331 on Apr 15, 2014

Helps my liver, along with DIM by Source Naturals, to break down estrogen, prevent acne, and knock out PMS.

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