Life Extension, Super K with Advanced K2 Complex, 90 Softgels (Discontinued Item)
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- Promotes Arterial Health and Healthy Bones
- Dietary Supplement
Super K with Advanced K2 Complex
An abundance of human clinical data reveals that vitamin K plays a critical role in maintaining healthy bone density by facilitating the transport of calcium from the bloodstream into the bone. Vitamin K is also required by calcium-regulating proteins in the arteries. Matrix Gla-protein (MGP) is a vitamin K-dependent protein, and it must be carboxylated to function properly. Poor vitamin K status leads to inactive uncarboxylated MGP (ucMGP), which accumulates at sites of arterial calcification. Since MGP is a potent local inhibitor of arterial calcification, MGP is important in relation to the health of the entire cardiovascular system. Without adequate vitamin K, calcium in the blood can bind to the arterial wall resulting in calcification. As people age, even a subclinical vitamin K deficiency can pose risks to the vascular system. Poor vitamin K status also results in increased circulating levels of undercarboxylated osteocalcin that is shown to be associated with increased bone loss in postmenopausal women.
Humans get most of their vitamin K from green vegetables in the form of vitamin K1. The problem is that K1 is tightly bound to plant fiber and only a small fraction absorbs into the bloodstream.
Vitamin K2 (menaquinones) is found in meat, eggs, and dairy products and is also made by bacteria in the human gut, which provides a certain amount of the human vitamin K requirement. Human studies show that vitamin K2 is up to ten times more bioavailable than K1. Vitamin K2 remains biologically active in the body far longer than K1. For instance, K1 is rapidly cleared by the liver within eight hours, whereas measurable levels of K2 (MK-7) have been detected 72 hours after ingestion.
The Rotterdam Heart Study, a large-scale, well-controlled clinical trial that tracked 4,800 participants for seven years, revealed that participants who ingested the greatest quantities of vitamin K2 in their diet experienced a better cardiovascular condition than people who ingested the least. High intakes of vitamin K2 also corresponded to less calcium deposition in the aorta, whereas participants who ingested less K2 were more likely to show moderate or severe calcification. Animal studies suggest vitamin K intake not only blocks the progress of further calcium accumulation, but also induces 37% regression of preformed arterial calcification.
Ideal Forms of Vitamin K2
In recent years, two forms of vitamin K2 have been extensively researched and the findings reveal vastly improved effects compared to K1. The MK-4 form of vitamin K2 is the most rapidly absorbed and is now routinely used in Japan to maintain healthy bone density. MK-4, however, only remains active in the blood for a few hours. The MK-7 form of K2, on the other hand, remains bioavailable to the human body over a sustained 24-hour period24 and to higher levels (seven- to eightfold) during prolonged intake. Both MK-4 and MK-7 have demonstrated remarkable health benefits when studied in human populations.
The Most Complete Vitamin K Formula
Vitamin K1 is the form found in plants and vegetables and should be part of most people’s daily supplement regimen. Even more important is inclusion of the MK-4 and MK-7 forms of vitamin K2.
Based on data substantiating the long-acting effects of MK-7, it is now possible to ingest fewer total micrograms of vitamin K but achieve far higher sustained blood levels of this critical nutrient.
The latest Super K with Advanced K2 Complex formula provides vitamin K1 and the MK-4 and MK-7 forms of vitamin K2 in just one daily softgel. The virtue of this formula is that it provides the precise amount of the long-acting MK-7 form of vitamin K2 that recent human studies have shown provides optimal K2 levels over a 24-hour period. The MK-4 is included to provide the rapid increase in vitamin K blood levels that may account for its beneficial effects in certain studies.
Read the entire label and follow the directions carefully prior to use.
Take one (1) softgel daily with food, or as recommended by a healthcare practitioner.
Extra virgin olive oil, gelatin, glycerin, beeswax, purified water, carob color.
Caution: If you are taking anti-coagulant or anti-platelet medications, or have a bleeding disorder, consult with your healthcare provider before taking this product.
- Keep out of reach of children
- Do not exceed recommended dose
- Do not purchase if outer seal is broken or damaged
- When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.
Store tightly closed in a cool, dry place.
|Serving Size: 1 Softgel|
|Amount Per Serving||%Daily Value|
|Vitamin C (as Ascorbyl palmitate)||10 mg||17%|
|Vitamin K activity||2200 mcg||2750%|
|Vitamin K1 (as phytonadione)||1000 mcg|
|Vitamin K2 (as menaquinone-4)||1000 mcg|
|Vitamin K2 (as menaquinone-7)||200 mcg|
|**Daily Value not established.|
iHerb Customer Reviews
Taking calcium supplements without K2 can improve bone strength, but it will also INCREASE THE RISK OF HEART DISEASE because only some of the calcium is deposited in the bones, where it is needed. Some of it is expelled via urine (which is why mainstream doctors recommend such high daily amounts of it) but the rest--dangerously--is packed around organs, where it does not belong and where it will do you harm. If deposited around the heart, it will increase your risk of heart disease; if deposited around the kidneys, it will increase the risk of kidney stones; if around the gallbladder, the risk of gallstones, etc. So you need to (1) take K2, which will deposit the calcium in your bones, where it belongs; (2) make sure you get enough D3 (from the sun whenever possible, then from supplements at other times), because it works synergistically and it will help your body absorb the calcium you ingest, whether from the diet or from a pill; and (3) reduce any calcium supplements you take, because once you have enough K2 and D3 your body will be able to use any calcium you ingest (instead of peeing it out and/or packing it around vital organs). You should also make sure you get enough magnesium if taking calcium, just don't take the two together because one blocks the absorption of the other. Happy bone health!
I've been taking the above for about 2 years to help calcium that I take to be absorbed. I had been diagnosed with osteopenia awhile back and I recently had a bone density test and was diagnosed as normal. I believe it helped to achieve that diagnosis.
DISCONTINUED? NO iHERB DECIDED TO NO LONGER STOCK IT!!! WHY IS THAT???
Posted by Reviewer1304673 on Feb 16, 2016
Apparently discontinued doesn't mean no longer made (as per my dictionary). By discontinued iHerb means they decided to no longer stock it nor do they stock any comparable product. It is still listed on the manufacturers site as available for order so WHY HAVE YOU STOPPED STOCKING IT???
Posted by 5161993927419304148 on Jan 18, 2016
This is a great product, it's a shame that is has been discontinued. I hope you're able to bring it back! I'd rather buy my supplements from the same place, and not have to visit multiple sites!
Why is this product discontinued???
Posted by Reviewer2407575 on Dec 25, 2015
I'm disappointed that iHerb has discontinued carrying this product! I would so much rather buy all my supplements in one place...
Posted by 5587173956062915737 on Oct 19, 2015
I just wanted to be more healthy, but It works very slow