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Now Foods, SAM-e (S-Adenosyl-L-Methionine), 100 mg, 60 Tablets

By Now Foods

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In Stock
  • Product Code: NOW-00136
  • UPC Code: 733739001368
  • Package Quantity: 60 Tablets
  • Dimensions: 2.1 x 2.1 x 3.7 in, 0.3 lbs (0.14 kg)

Product Overview

  • Nervous System Support
  • Supports Cartilage Production
  • Enteric Coated
  • A Dietary Supplement
  • Vegetarian/Vegan
  • GMP Quality Assured

SAMe (S-adenosylmethionine), a compound native to the body, is a critical component of many biochemical reactions, including those that affect brain biochemistry and joint health. SAMe is critical for the synthesis of neurotransmitters, is important for energy production in the brain, contributes to the maintenance of healthy cell membrane function, and influences cartilage metabolism. NOW SAMe is enteric-coated, which makes it very well tolerated and protects it from degradation.

Suggested Use

As a dietary supplement, take 1 tablet 2 to 4 times daily, preferably on an empty stomach.

Refrigeration recommended after opening.

Other Ingredients

Cellulose, croscarmellose sodium, magnesium stearate (vegetable source), stearic acid (vegetable source), silica, ascorbic acid, citric acid and enteric coating (cellulose, triethyl citrate, menthacrylic acid).

Not manufactured with wheat, gluten, soy, milk, egg, fish, shellfish or tree nut ingredients. Produced in a GMP facility that processes other ingredients containing these allergens.


Do not eat freshness packet. Keep in bottle.

Caution: For adults only. Individuals with bipolar (manic) depression and those with anxiety disorders should not take SAMe unless under professional medical supervision. Consult physician if pregnant/nursing, taking medication, or have a medical condition. Keep out of reach of children.

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Supplement Facts
Serving Size: 1 Tablet
  Amount Per Serving %DV
SAMe (S-Adenosyl-L-Methionine) (from 200 mg of S-Adenosyl-L-Methionone Disulfate
100 mg *
* Daily Value not established.

iHerb Customer Reviews

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1 Stars

Excellent stuff!

Posted by Reviewer2767188 on Jul 11, 2008

I find this strength of SAM-e to be very helpful for my CFS. All the tablets are enteric coated and aren't too strong. More gentle than over powering. Seems to helps clear the head of brain fog too.

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5 people found the following review helpful

A lifesaver

Posted by Reviewer2903784 on Mar 26, 2009

We use this for my son who is an undermethylator--can be assessed by looked at histamine levels in the blood. A higher dose would usually be recommended for his size (9 years old, average weight), but we found it was too much. And since SAMe is usually enterically-coated so it gets to the right part of the gut, cutting a larger tablet was not a good idea. This size is perfect for us.

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3 people found the following review helpful

Easier to take!

Posted by Reviewer3336818 on Jun 11, 2010

Before using the 100 mg Now Foods SAME-e I tried taking another brand (not sold at iHerb) in the typical 200 mg dose, and had a big problem. I have trouble swallowing and that big "horse pill" got stuck in my esophagus and wouldn't budge. Being "enteric coated", SAM-e tablets don't dissolve until they reach your stomach, so that thing was there for hours! I'll spare you the details, but it was not good. So I was happy to find a 100 mg (i.e., smaller) tablet. I just take two of them instead of one 200 mg tablet. And from what I'm able to tell after using them a few weeks, they work as advertised. So, I'm pleased.

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3 people found the following review helpful

Sam-e rocks

Posted by Reviewer2814550 on Feb 17, 2010

Sam-e has been nothing but a blessing for my entire family, including my parents who are in their 70's. I take it first thing in the morning on an empty stomach. My world goes from bleak to hopeful on Sam-e. It is important to refrigerate it if it is not in blister packs. It does not help with my anxiety so I take 200mg L-theanine for that and it works wonders.

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2 people found the following review helpful

Great for nerve pain

Posted by Reviewer1641883 on Aug 29, 2012

Excellent for nerve pain, & this Now Foods is the only brand that I found that have a lower 100mg SAMe, which is what I was looking for. Other companies do much higher strengths. I like to start on lower doses,when trying new supplements, to test their affect. 100mg seems to be quite enough for me & works great! Will buy again,

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2 people found the following review helpful

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