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Solgar, Folate (As Metafolin), 400 mcg, 100 Tablets

By Solgar

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  • Product Code: SOL-01941
  • UPC Code: 033984019416
  • Package Quantity: 100 Tablets
  • Dimensions: 3.5 x 2 x 2 in, 0.3 lbs (0.14 kg)
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Product Overview

  • Since 1947
  • Heart Health
  • Gluten, Wheat & Dairy Free
  • Suitable For Vegetarians
  • Kosher Parve
  • Dietary Supplement

Folic Acid must first be converted to its active form by a series of biochemical steps, before it is able to be used by the body. Metafolin (L-methylfolate) requires no conversion because it is bioidentical to the bio-active form. In other words, it is 'body-ready'. This can be useful for individuals whose bodies have difficulty converting folic acid to its active form. The active folate in this formulation promotes heart health. It also supports a healthy nervous system and the formation of healthy red blood cells.

Suggested Use

As a dietary supplement for adults, take one (1) tablet one to two times daily, preferably at mealtime, or as directed by a healthcare practitioner.

Other Ingredients

Mannitol, microcrystalline cellulose, vegetable stearic acid, vegetable cellulose, silica, vegetable magnesium stearate.

Free Of: Gluten, wheat, dairy, soy, yeast, sugar, sodium, artificial flavor, preservatives and color.


If you are pregnant, nursing, taking any medications or have a medical condition, please consult your healthcare practitioner before taking any dietary supplement. Keep out of reach of children. Store at room temperature. Do not use if outer bottle seal is missing, torn or damaged in any way.

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Supplement Facts
Serving Size: 1 Tablet
  Amount Per Serving %DV
Folate (as L-methylfolate as Metafolin) 400 mcg 100%
DV = Daily Value
Provides a dietarily insignificant amount of sugar alcohol

iHerb Customer Reviews

5 Stars
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probably the right dose

Posted by Reviewer1612414 on Apr 06, 2010

Folate has been recommended to help in depression and may have a calming effect. There is a prescription form of Metafolin called Deplin which comes in 8 milligrams (or 8000 micrograms), but there is a disclaimer that Metafolin may aid in the growth of tumors/cancer, especially in the GI tract (which makes sense because Metafolin is used in DNA synthesis and rapidly dividing cells need to make DNA). Note it won't cause cancer, but it may aid in the growth/spread of a tumor if it is there. Also if you are going through cancer treatment, don't take folate supplements. Anyways, if you want to see if Metafolin may help your symptoms, this could be a good starting dose with less risk.

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36 people found the following review helpful

Excellent product.

Posted by Reviewer1572597 on Aug 27, 2010

I ordered these because I read somewhere that it can help with depression. Within the first two days I felt completely different. I immediately felt so happy and at peace with my self...something I haven't experienced in many years! I have taken many prescription medications for depression and none of them worked. It seems that I simply had a folic acid deficiency and I'm not crazy! I really recommend any female who is experiencing sadness or depression to try it. Also, the pills are really tiny and are easy to swallow.

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15 people found the following review helpful

strong and effective but lowers zinc

Posted by 5280615812874896036 on Apr 21, 2015

Prenatal care, alongside Inositol. Absolute cure for depression. In general, Folate reduces birth defects, enhances digestion, helps prevent anemia, elevates serotonin in the brain, prevents heart disease, and is needed for cellular repair. Its lack usually manifests in heart palpitations, persistent fatigue, insomnia, depression, bleeding gums,in being forgetful, being lightheaded, being irritable, have trouble concentrating, in loss of appetite, and loss of weight. However it lowers zinc, so it must be taken as well.

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8 people found the following review helpful


Posted by francesjoan on Aug 26, 2010

A retired gynecologist recommends metafolin for healthy aging. I had some close relatives with dementia so this is part of my brain healthy supplements.

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6 people found the following review helpful

The ultimate in methylfolate

Posted by Reviewer2798647 on Jul 25, 2012

Most people and Doctor's don't know the difference between folate/folinic acid and methylfolate. Methylfolate is the most active form of folate and the only one that crosses the blood-brain-barrier. No wonder it is one of the most novel treatments for depression, anxiety, CFS and many other nervous system problems.

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6 people found the following review helpful

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