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- Dietary Supplement
- P-5'-P (Pyridoxal-5'-Phosphate)
- Promotes a Healthy Nervous System
In order for vitamins to be utilized by the body, they must first be converted into their active coenzyme forms. This more potent Coenzymated B-6 is in its active form and ready to go to work immediately. Pyridoxal-5'-Phosphate (PLP or P-5'-P) is the main metabolically active coenzyme form of vitamin B-6. It is primarily in the liver that P-5'-P is synthesized from pyridoxine, with the help of enzymes that require B-2, zinc and magnesium for their activity. P-5'-P activates over 100 enzymes, many of which are involved in the conversion of amino acids into the neurotransmitters dopamine, norepinephrine and serotonin. P-5'-P is also required for the synthesis of the hemoglobin molecule and plays an important role in regulating homocysteine levels.
1 tablet daily.
Microcrystalline cellulose, stearic, acid and silica.
Suitable for vegetarians and HYPOALLERGENIC: contains no yeast, dairy, egg, gluten, corn, soy or wheat. Contains no sugar, starch, salt, preservatives, or artificial color, flavor or fragrance.
If you are pregnant, may become pregnant, or breastfeeding, consult your health care professional before using this product.
Do not use if either tamper-evident seal is broken or missing. Keep out of the reach of children.
|Serving Size: 1 Tablet|
|Amount Per Serving||%DV|
|Vitamin B-6 (from 100 mg pyridoxal-5'-phosphate [Coenzymated])||67 mg||3,350%|
I was having issues with NON-coenzymated B6 causing wheezing, headaches and moodiness among other things - regardless of the brand/dose or whatever else I was/wasn't eating/taking. So I thought I'd give coenzymated B6 a try given the number of glowing reviews and good press it receives within the health/nutrition community. However - I had the same issues with half a tablet of this coenzymated B6. B6 is an antagonist of IODINE, SODIUM, MANGANESE, SILICA and COPPER - low levels of these essential nutrients can cause wheezing, headaches and other problems such as hyper/hypothyroidism, hair loss, etc etc. Over time B6 will also raise magnesium which may not be beneficial - magnesium antagonises iodine, silica, manganese, cobalt, sodium, etc. Adding more of these nutrients won't correct the issue. B6 is also an inhibitor of 5-alpha reductase, which can be an issue when activity of this enzyme is low, e.g. other nutrients that also inhibit this enzyme include alpha-linolenic acid, oleic acid, linoleic acid, B2, zinc (think hormonal disorders, hair loss). After some positive results, I did take B6 in the past (in combo with other vit B's) - not excessive doses and not for long periods of time either. However, after struggling to correct the imbalances it caused, I do not recommend it as a long-term strategy for anyone, regardless of issue/reason for taking it - it's simply not designed for long-term use at mega-doses (by mega-dose I mean anything above 10mg per day). If B6 works for you I strongly suggest looking into why rather than continuing long-term use - e.g. if it helps with water retention or hormonal issues, look at other nutrients or areas of diet that might be disrupting these. While B6 might seem like a heaven-sent quick-fix, I'd hate for anyone to go through the same as me after taking B6 for any period of time. If this review was helpful to you, please click YES below - thank you. For reviews of all the products I have purchased from iHerb, please click my username above.
I have been using this product for a year now for no 3 year old daughter who has epilepsy. I stopped for a while on the advice of doctors to see what the impact was. And it was dramatic, she become lethargic and had more seizures. When I reintroduced it, it was remarkable, which is always in when I restart. She is alert again, has less seizures and is very bright. I recently put in another order, and this time there was less colouring in which is great as it can get really messy when it is not swallowed straight away. Great product, a bit bitter, but wouldn't be without it. We can't get in the UK, it is delivered within a few days which is very reassuring. Good product and Excellent Company.
Pill size and consistency changed recently, seems much less potent
Posted by Reviewer1003688 on Sep 08, 2015
I've used this on and off for a few years. Recently it changed. The ond pill would actually dissolve under my lip. This one just turns to mush and stays there all day. I don't really feel this new pill doing anything. 9/8/2015
Posted by Reviewer1055106 on May 25, 2015
Great for water retention. Make sure not to exceed recommended dose. Too high amount of B6, more than 600 mg, can cause nerve damage. I take 1-2 tablets when needed and inbetween an organic multiple vitamin B tablet, super B complex by Synergy Company, available at Iherb.
Posted by 4838135463888010802 on May 12, 2015
This bottle will last a looong time.
Source Naturals, Coenzymated B-6, 100mg, 60 tablets
Posted by Reviewer2621911 on Dec 05, 2014
just started to take this so cannot rate it yet.