Source Naturals, SAM-e (S-Adenosyl-L-Methionine), 400 mg, 30 Enteric Coated Tablets
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- Supports Joint Comfort, Function and Mobility
- Double Strength
- Dietary Supplement
Source Naturals SAMe is a stable, bioavailable form of S-adenosyl-L-methionine. These tablets are enteric coated and blister packed to prevent breakdown and inactivation of the ingredients.
Dozens of clinical studies have demonstrated that SAMe supports joint comfort, function and mobility in the spine, hips and knees. It is important to the joints because of its critical role in cartilage formation. SAMe helps to form proteoglycans, which are used to renew the matrix of cartilage.
The studies also show that SAMe helps support a positive outlook. It is able to cross the blood-brain barrier, where it affects the synthesis and activation of various proteins, such as neurotransmitters. SAMe also plays a role in transmethylation. Transmethylation reactions affect the synthesis, activation, and metabolism of various biological molecules. Some compounds that SAMe methylates are phospholipids. This is a fundamental step in the mediation of cell to cell communication.
SAMe is present in every living cell in the body and plays an important part in many critical cellular functions. However, levels of SAMe tend to decline with age.
1 tablet, 1 to 3 times daily. Take tablets on an empty stomach.
Cellulose, mannitol, hydroxypropyl methylcellulose phthalate, citric acid, silica, stearic acid, glyceryl triacetate, sodium starch glycolate, modified cellulose gum, titanium dioxide and yellow ochre.
Suitable for vegetarians. Contains no yeast, dairy, egg, gluten, soy or wheat. Contains no sugar, salt, preservatives, or artificial flavor or fragrance.
If you are pregnant, may become pregnant, breastfeeding or are taking antidepressant medication, consult your physician before using this product. Use this product under medical supervision if you have bipolar disorder. In a small percentage of people this product may cause nausea or gastrointestinal upset. If you experience discomfort, discontinue use.
Do not use if either tamper-evident seal is broken or missing.
Keep out of the reach of children.
|Serving Size: 1 Tablet|
|Servings Per Container: 30|
|Amount Per Servings||% Daily Value|
|SAMe (s-adenosyl-L-methionine) from 800 mg of SAMe disulfate tosylate||400 mg||†|
|†Daily Value not established.|
Excellent product. In Europe, this supplement is a prescription product and is the #1 prescription for depression. In their clinical studies, they prescribe 1200 to 1600 mg daily (that is 3 to 4 of the double strength each day). I mention this to help others, because at this dosage it really, really helps beat some of my fibromyalgia and arthritis pain, gives some mental alertness and a better mood, and it also helps protect the liver when you have to take other prescription meds that might comprimise liver function. At iherb's price, it costs about $60 a month at the 3 daily dose, which is worth it for the difference it makes. I can always tell the decline in health when I let my supply run out. Best of Health to you!
I noticed they have some questionable ingredients, namely, modified cellulose gum and hydropropyl mehylcellulose phthalate. I have heard very bad things about phthalates and have been trying to avoid them. I tried to contact the company and they gave me an email to which there has been no response.
I am definitely happier after using this product for 2 weeks
Posted by 5375783669111175622 on Oct 18, 2016
I can vouch that it worked for me. Two and a half weeks later I am feeling more optimistic and steadier. Pre menopausal blues have started to lift. I am hesitant to recommend it as a natural anti depressant because I know it does not work for everyone. In saying that, it worked for me and I am grateful.
Posted by 5586896955355261579 on Jan 08, 2014
Great product, very effective. Been using for a month and will continue to use. Has improve my general well being. Mood, mobility and funny enough my skin complexion.
Posted by 5219846649855951187 on Dec 27, 2013
Find it helps distress and relax, use it along with St Johns Wort, is just the extra boost needed to help cope with looking after both wife and father-in-law, who both have cancer.
Posted by 5419148741403620066 on Oct 18, 2013
good quality at a good price
Posted by Reviewer3272543 on Feb 14, 2013
Unfortunately, I experienced extreme nausea from this supplement and had to throw it out after trying it twice to be sure. Although I have a history of migraines and sensitivity to ingredients, nausea is a common side effect of SAMe. It's recommended to take on an empty stomach for best absorption and on a full stomach if nausea happens. I felt so ill I did not want to even try it on a full stomach. Wish there had been a trial size.