Thorne Research, 5-MTHF, 5 mg, 60 Veggie Caps
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- Dietary Supplement
Folic acid must be converted to its active forms to be used by the body. This is a multi-step biochemical process that occurs in the intestines and liver. In the presence of intestinal or liver dysfunction this conversion may not occur sufficiently enough to meet the body's needs. Furthermore, up to 60-percent of the U.S. population may have a genetic enzyme defect that makes it difficult for them to convert folic acid into active 5-MTHF. For these individuals and many others, 5-MTHF supplementation may be a more effective method of folate repletion.
5-MTHF is an essential cofactor in the metabolism of the amino acid metabolite homocysteine. 5-MTHF also must be present in sufficient quantity for normal production of the neurotransmitters serotonin, melatonin, dopamine, epinephrine, and norepinephrine. These functions make 5-MTHF critical for both cardiovascular function and mood support.
Take 1 capsule two to three times daily or as recommended by your health-care practitioner.
Microcrystalline cellulose, hypromellose (derived from cellulose) capsule, leucine, silicon dioxide.
Tamper Evident: Use only if bottle is sealed.
If pregnant, consult your health-care practitioner before using this product.
Store tightly sealed in a cool, dry place.
|Serving Size: One Capsule|
|Amount Per Serving||%DV|
|Folate (as L-5-Methyltetrahydrofolate)||5 mg||1,250%|
|Daily Value (DV)|
iHerb Customer Reviews
High concentrates of Folic Acid have been shown to aid anti-depressants in making more serotonin available to the body. I was using a prescription version called Deplin but the cost was too high for me. I've found this produce to give the same benefits. On days when I don't take it I notice more depression, so I take one daily. And you can't get the benefit by buying Folic Acid at the drugstore. One would have to consume dozens a day for the same or lesser benefit.
I had been trying desperately to lower my homocysteine with a high dose of ordinary folate. It had worked in 2004, but not any more. Then I read about 5-MTHF and thought that 1 mg should do it. Disappointment again. Then I made a mistake and ordered 5-MTHF in the 5 mg strength. That did it. My number is 8.5 where I want it to be. I may have to toggle back and forth between the two strengths because it can be unwise to lower homocysteine too much.
outstanding quality and results
Posted by 4939929625851837239 on May 03, 2016
In combination with Kirkman Labs DMG this led to our 5yo autistic son regaining his speech abilities.
Posted by 4770635144223515602 on May 18, 2015
The time frame for postage was spot on. Most efficient. I will definitely purchase from iHerb again. Thank you so much.
Inferior to solgar brand metafolin
Posted by 5357228986904339794 on Mar 30, 2015
I found that this product to be extremely inferior to the solgar brand metafolin. I bought this thinking it's better value for money and it's more convenient then popping 10 tabs of solgar a day. I however dipped into a deep depression with crushing anxiety after 1 week from switching from solgar to this brand. Would not recommend to any with the 5-MTHFR gene mutation.
Posted by 4669966199893780123 on Apr 10, 2014
This is much better than the 1mg it makes such a difference. A great product so much more concentration.
Expensive, but best available
Posted by Reviewer1497090 on Jan 16, 2014
This is a good high strength product from a reliable brand. Have looked, but not found anything as good. Capsule size is on the smaller side (good for kids), as we use this for Autism support (1 a day, with B12 shots, etc.).