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Thorne Research, Betaine HCL & Pepsin, 625 Veggie Caps (Discontinued Item)

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Out of Stock - Discontinued
  • Shipping Weight: 1.42 lbs (0.64 kg)
  • Product Code: THR-41402
  • UPC Code: 693749414025
  • Package Quantity: 625 Veggie Caps
  • Dimensions: 3.7 x 3.7 x 6.6 in, 1.2 lbs (0.54 kg)
  • This item is being replaced by THR-00469. New capsule count.

Product Overview


  • Dietary Supplement
  • Hypoallergenic

Indigestion affects millions of people every day. For some, eating fatty foods can bring on heartburn. For others, simple carbohydrates (like bread and pasta) may cause gas and bloating. And for other individuals, spicy foods can cause them grief. Although what we eat greatly influences the frequency and severity of indigestion, this discomfort could be related to an underlying problem – poor digestive enzyme activity.

Situations such as illness, gall bladder removal, overuse of antacids, and normal aging can contribute to insufficient secretion of stomach acid, pancreatic enzymes, and bile, and can adversely affect digestive enzyme activity and lead to occasional heartburn, gas, bloating, and other forms of gastrointestinal discomfort.

Maldigestion can lead to digestive problems and poor absorption of nutrients, resulting in vitamin deficiencies (particularly fat-soluble vitamins like vitamins A, D, E, and K). Food allergies can develop when inadequately digested proteins are absorbed through the gut. As large proteins are absorbed intact, the body might recognize them as foreign and create antibodies to them, resulting in an allergic response to the food. An individual who has frequent indigestion should make sure to have adequate enzyme support.

Hydrochloric acid secretion in the stomach does several positive things. It assists protein digestion by activating pepsinogen to pepsin, it renders the stomach sterile against ingested pathogens, it inhibits undesirable overgrowth in the small intestine, and it encourages the flow of bile and pancreatic enzymes. Hydrochloric acid also facilitates the absorption of a number of nutrients, including folate, vitamin B12, ascorbic acid, beta-carotene, iron, and some forms of calcium, magnesium, and zinc. Numerous studies have shown hydrochloric acid secretion in the stomach declines with advancing age. Overuse of antacids can also lead to low levels of hydrochloric acid in the stomach, which can result in poor protein digestion. Thorne offers hydrochloric acid and pure pepsin from a porcine source. Unlike many supplement companies, the pepsin utilized in Thorne's product is pure, undiluted, and lactose-free.

Suggested Use

Take 1-2 capsules with each meal or as recommended by your health-care practitioner.

Other Ingredients

Hypromellose (derived from cellulose) capsule, leucine, silicon dioxide.

Betaine Hydrochloride derived from a non-plant source. This product is not diluted with lactose.


Tamper Evident: Use only if bottle is sealed. Store tightly sealed in a cool, dry place.

Individuals with porcine allergies should not take this product.

Supplement Facts
Serving Size: Two Capsules
Serving Per Container: 312
Two Capsules Contains: Amount Per Serving % DV
Betaine Hydrochloride† 1.04 g *
Pepsin (Porcine)†† 40 mg *
*Daily Value (DV) not established.
†Equivalent to 16 grains.
††Equivalent to 3.2 grains (200 mg) of Pepsin 1:3,000 potency.
iHerb Customer Reviews

great product & great value

Posted by Reviewer1794079 on Dec 30, 2013

it comes in capsules. easy to swallow & more effective. believe it or not, it seems to help my sinus.

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Posted by 4614833340513791876 on Aug 16, 2013

I believe this to be one of the most important supplements alongside a probiotic and digestive enzyme. This has product really helped with the bloating and allows me to eat more,whereas before supplementing I would eat a small breakfast and not even want lunch or dinner.

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Helps to absorb nutrients from food

Posted by Reviewer2098658 on Aug 04, 2013

Nothing seemed to improve my extremely low iron level until I started taking this product. Doctors could not explain why (most of them are useless anyway). As it turned out, I had very low acidicy in my stomach, so most nutrients were not absorbed properly, including iron and calcium. This product has helped immensely.

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Great product

Posted by 5193939841330322921 on Oct 31, 2012

I have had digestion and constipation problems for years. No more laxatives and my skin and hair are no longer oily all the time.

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The best!

Posted by Jodi-Hummingbird on Sep 22, 2012

Love the huge pill count and the fact this product is dairy free. The pills are also easy to swallow as they aren't too big. I take 5 - 7 with my evening meal and they really help digestion (along with kefir, sauerkraut and a digestive enzyme product). I wish all the supplements I took came in bottles of 600+ capsules!

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