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Thorne Research, Indole-3-Carbinol, 60 Veggie Caps

By Thorne Research

MSRP:
$27.61
Our Price:
$27.60
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Out of Stock
  • Product Code: THR-74903
  • UPC Code: 693749749035
  • Package Quantity: 60 Veggie Caps
  • Dimensions: 3.8 x 2 x 2 in, 0.1 lbs (0.05 kg)
  • Important Note:

    The bottles of this item may have some dis-colorization due to oxidation. However, we have been re-assured by the manufacturer that this does NOT affect the product itself by anyway. - iHerb

Product Overview

Description
  • Dietary Supplement
  • Hypoallergenic
  • To Support Estrogen Metabolism
  • Maintains Optimal 2-Hydroxy/16-Hydroxy Estrogen Ratios
  • Found in Cabbage Family Vegetables, it's a Source of DIM
  • Nutritional Support for Liver Detoxification
  • Made Without Flowing Agents that can Inhibit Bioavailability

Indole-3-carbinol (I3C) is a compound found in high concentrations in vegetables of the Brassica family, including broccoli, cauliflower, Brussels sprouts, and cabbage.

As a dietary supplement, I3C provides key nutritional support for liver detoxification. It also plays an important role in supporting female reproductive health. The majority of ingested I3C is absorbed in the small intestine as diindolylmethane (DIM), which is thought to be the primary contributor to I3C's beneficial properties. DIM has been shown to selectively bind to estrogen receptors and may act as an estrogen antagonist at physiological concentration.

In the liver, I3C promotes the metabolism of estrogen and increases the ratio of 2-hydroxy estrogen to 16-hydroxy estrogen. The 2-hydroxy estrogens, less active than the 16-hydroxy estrogens, generally are eliminated more rapidly from the body. One prospective study found postmenopausal women with the most favorable urinary 2:16-hydroxyestrone ratio were most likely to maintain good female health.

Preliminary studies have examined the efficacy, safety, and optimal supplementation of I3C. A 12-week phase I trial conducted on 17 women found a 66-percent increase in urinary 2:16-hydroxyestrone ratio with administration of 400 mg I3C daily.

Suggested Use

Take 1 capsule one to two times daily or as recommended by your health-care practitioner.

Other Ingredients

Hypromellose (derived from cellulose) capsule, microcrystalline cellulose, leucine, silicon dioxide.

Warnings

Tamper Evident: Use only if bottle is sealed.

If pregnant, consult your health-care practitioner before using this product.

Store tightly sealed in a cool, dry place.

Visit Manufacturer's Website
Supplement Facts
Serving Size: One Capsule
  Amount Per Serving % DV
Indole 3-carbinol / Diindolylmethane (DIM) complex 200 mg *
* Daily Value (DV) not established.

iHerb Customer Reviews

5 Stars
4 Stars
(5)
3 Stars
(0)
2 Stars
(3)
1 Stars
(1)
 

Great product with no fillers

Posted by 5314027903119101750 on Mar 21, 2016

This is the purest I-3-C currently available on i-Herb and represents great value for money

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Good

Posted by Reviewer2800481 on May 29, 2014

Have just started taking for breast protection and hormone balancing

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My doctor prescribed for high estrogen levels

Posted by pareedus on May 26, 2014

My doctor tested me and my estrogen was 4 times what it was supposed to be, with the side effects that come with that. I have been taking this for a couple of years, and have not been re-tested, but I do feel less angry and prone to fly off the handle. I don't know why other reviewer have said this product 'tastes bad' or 'smells funny'. It's a gelatin capsule- you don't chew it, you swallow it! It's fine to me, I haven't noticed those things and I am focused on the benefits.

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I3C

Posted by adechamplain on Jan 02, 2014

Indole 3 Carbinol is a great compound found in surfuric foods like broccoli , cabbage, kale, and so on. Helps control oestrogen levels but can also inhibit the thyroid so worth checking with blood tests every now and then. I only started two weeks ago so might have to give this a longer try to see the effects.

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bad smell

Posted by 5108463461198250398 on Feb 24, 2013

I ordered this product and just started to use, I noticed that it has bad smell. I am not sure may be my product came spoiled or it is normal smell of this product.

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