Thorne Research, Methyl-Guard, 180 Veggie Caps
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- Dietary Supplement
Maintaining a normal plasma homocysteine level has joined elevated cholesterol and triglyceride levels as a leading concern for maintaining good cardiovascular health. Plasma homocysteine levels are also associated with maintenance of bone, female reproductive, cognitive, and neurological health. Numerous studies advocate the lowering of plasma homocysteine levels via nutritional supplementation. A number of biochemical imbalances that can raise homocysteine levels can be addressed by supplementing with the appropriate nutrient cofactors. For example, folic acid (as L-5-methyltetrahydrofolate), vitamin B12 (as methylcobalamin), and betaine (trimethylglycine) are involved in recycling homocysteine to the amino acid methionine, while the breakdown of homocysteine into the beneficial amino acids cysteine and taurine can be facilitated by pyridoxal 5'-phosphate (the active form of vitamin B6). Studies have shown these nutrients can help maintain normal plasma homocysteine levels.
In addition to the beneficial homocysteine effects of the ingredients in Methyl-Guard, folic acid has been shown to help maintain the normal function of the arterial walls, allowing them to dilate more readily and enhance circulation. Homocysteine levels can be increased in individuals in which the enzymatic reaction responsible for converting folic acid to the active methyl donor L-5-methyltetrahydrofolate (5-MTHF) does not function properly; therefore, Methyl-Guard contains 400 mcg of active 5-MTHF per capsule.
Maintaining normal homocysteine is important for good cognitive health. A deficiency in homocysteine-metabolizing cofactors is commonly seen in the elderly, which can result in an increase in homocysteine levels with advancing age. Vascular structures can be adequately maintained when plasma homocysteine levels are normal by elevated homocysteine, thus helping to maintain cognitive health. Elevated homocysteine levels associated with aging, as well as low levels of folic acid and vitamins B6 and B12, can result in the decreased methylation of numerous substances, including DNA and proteins, decreasing the integrity of vascular structures and neurons. Providing the nutritional cofactors for homocysteine metabolism provides support for a healthy brain.
Methyl-Guard was the first dietary formula on the market to promote homocysteine metabolism and is the only one that contains the active, body-ready forms of the homocysteine-metabolizing nutrient cofactors.
Take 3 capsules two times daily or as recommended by your health-care practitioner.
Hypromellose (derived from cellulose) capsule, CalciumCitrateLaurate, silicon dioxide.
Tamper Evident: Use only if bottle is sealed.
If pregnant, consult your health-care practitioner before using this product.
Store tightly sealed in a cool, dry place.
|Serving Size: Three Capsules|
|Serving Per Container: 60|
|Three Capsules Contain:||Amount Per Serving||% DV|
|Vitamin B6 (as Pyridoxal 5'-Phosphate)||20.4 mg||1,020%|
|Folate (as L-5-Methyltetrahydrofolate from L-5-Methyltetrahydrofolic Acid, Glucosamine Salt)||1.2 mg||300%|
|Vitamin B12 (as Methylcobalamin)||1.2 mg||20,000%|
|Betaine Anhydrous (Trimethylglycine)||1.8 g||*|
|*Daily Value (DV) not established.|
iHerb Customer Reviews
Product was recommended by my family Doctor to help me delay the process of ageing and my difficulty with my memory. I am pleased to say the product has worked better than I expected.
I was really impressed with how fast my order arrived. I already use methyl guard and have for a while but I was paying double the price in Australia.
Posted by Happichique on May 09, 2016
I have an inherited genetic mutation (MTHFR) and this product supplies an all-in-one capsule thus taking away the need for several different medications to achieve the same result - love it!
Posted by 5030158663250493505 on Dec 14, 2015
Very happy with the speedy delivery and the price however I was wondering if anyone can tell me how long it took for you to feel the effects of taking this capsule. I am in my 5th week and I don't feel any better yet
Fibromyalgia, arthritis remedy
Posted by Reviewer1836572 on Aug 27, 2015
This is a new product for me. My friend informed me about its propensity to stave off painful fibromyalgia and arthritis. It works!
Posted by 4833458343424557664 on Jun 17, 2015
still taking this, although not sure why I was given it. Maybe to support liver function? don't know. No side effects so I'm still taking it.