Your Cart is Empty
But it doesn't have to be.
Continue Shopping.
Added to Cart
Cart Total:
Customers Also Bought:

Thorne Research, Niasafe-600, 180 Veggie Caps

Our Price:
You Save:
$0.01 (0)
Earn 5% Loyalty Credit ?

Sorry, this product is no longer in stock.

This product is already in your Wish List.

View Wish List

This product is now in your Wish List.

View Wish List
In Stock
  • Expiration Date: Jun 2018
  • Shipping Weight: 0.47 lbs (0.21 kg)
  • Product Code: THR-11402
  • UPC Code: 693749114024
  • Package Quantity: 180 Veggie Caps
  • Dimensions: 2.8 x 2.8 x 5.2 in, 0.4 lbs (0.18 kg)
Bundle Offer
Save $3.94 when you purchase these items today for only $53.35
Total: $57.29
Combo Discount: - $3.94
Together: $53.35

Sorry, this product is no longer in stock.

Product Overview


  • Dietary Supplement
  • Hypoallergenic
  • Inositol Hexaniacinate - a Safer, Non-Flushing Alternative to Niacin
  • Provides a Higher Amount of Niacin without the Flushing
  • Unlike Time-Release Niacin - Niasafe is Easy on the Liver
  • Supports Peripheral Vascular Circulation
  • Supports Lipid Metabolism

Niacin has long been used to support good cardiovascular health. It has been proven effective at helping to maintain already normal levels of cholesterol.

The side effects of high amounts of niacin that may occur range from flushing and itching to liver toxicity and impaired glucose tolerance. Therefore, the need for a safer approach to niacin supplementation resulted in the investigation of niacin esters. One of the most widely studied niacin esters is inositol hexaniacinate (IHN). In numerous trials IHN has been found to be virtually free of the side effects associated with conventional niacin therapy. Pharmacokinetic studies show the IHN molecule is absorbed intact and slowly hydrolyzed in the bloodstream, releasing free niacin and inositol and having a diminished impact on the liver. Maximum serum levels are reached approximately 10 hours after ingestion, thus allowing for a more delayed release of niacin that reduces the risk of flushing.

A review of the literature reveals numerous positive studies on the use of IHN to support good circulatory health, particularly the support of vascular circulation to the extremities.

Suggested Use

Take 1 capsule one to three times daily or as recommended by your health-care practitioner.

Other Ingredients

Hypromellose (derived from cellulose) capsule, leucine, silicon dioxide.


Tamper Evident: Use only if bottle is sealed.

If pregnant, consult your health-care practitioner before using this product.

Store tightly sealed in a cool, dry place.

Supplement Facts
Serving Size: One Capsule
  Amount Per Serving % DV
Niacin (as Inositol Hexaniacinate†) 540 mg 2,700%
Daily Value (DV)
†Does not cause flushing in many patients.
iHerb Customer Reviews

Can't get out of bed without it

Posted by Reviewer3017834 on Dec 20, 2013

Indispensable for mood, energy and liver function. Highly recommended.

Verified Purchase

Was this review helpful to you?

Don't get any red flushes

Posted by OssieA on Oct 16, 2011

Ordinary niacin gave me red rashes if I didn't eat enough when taking. This Niasafe doesn't do that.

Verified Purchase

Was this review helpful to you?


Posted by Reviewer1630744 on Sep 08, 2011

Wonderful product, have had no problems with it nor reactions from it.

Verified Purchase

Was this review helpful to you?


Posted by Reviewer3325914 on Jun 05, 2011

this is a good product. I didn't get any flushes after taking it, like I have done with other niacin products.

Verified Purchase

Was this review helpful to you?

Works good to lower LDL

Posted by Reviewer1840838 on Jun 04, 2011

This niacin works well to lower LDL....lowered mine. Thorne Research is a great brand - no bad fillers.

Verified Purchase

Was this review helpful to you?