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Thorne Research, Perfusia-SR, 120 Veggie Caps

By Thorne Research

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  • Product Code: THR-52502
  • UPC Code: 693749525028
  • Package Quantity: 120 Veggie Caps
  • Dimensions: 2.6 x 2.6 x 5 in, 0.3 lbs (0.14 kg)
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Save $6.00 when you purchase these items today for only $37.95


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Product Overview

  • Dietary Supplement
  • Hypoallergenic

Sustained-release L-arginine supports cardiovascular function, wound healing, and immune function – and is a biological precursor to nitric oxide.

L-arginine is a semi-essential amino acid involved in multiple areas of human physiology and metabolism. L-arginine significantly affects endocrine function and helps regulate the release of neurotransmitter chemicals, insulin, glucagon (which has the opposite effect of insulin; i.e., it raises blood sugar), and growth hormone. However, one of L-arginine's most compelling contributions to human physiology is its role as a biological precursor of nitric oxide. The vascular endothelium (lining of the arteries) creates nitric oxide from L-arginine, resulting primarily in blood vessel relaxation. This property is critical to maintaining good vascular health, heart health, reproductive health, and protection against oxidative damage.

Maintaining the natural, healthy functions of the vascular endothelium is dependent upon an adequate supply of L-arginine being available to these cells. As mentioned above, the conversion of L-arginine to nitric oxide is responsible for these functions by making the endothelial cells more resistant to oxidative damage and adhesion by otherwise harmful substances. Numerous studies have demonstrated that individuals with sufficient nitric oxide production by endothelial cells have the best opportunity to maintain already normal cardiovascular health.

In a large, double-blind trial that observed male reproductive health issues, 1.6 g L-arginine daily for six weeks resulted in improvement in reproductive health in those men with low nitric oxide metabolism.

Like most amino acids, L-arginine functions as a building block of proteins; however, its presence also appears to support wound healing. Numerous studies show L-arginine supplementation benefits wound healing time and strength of the tissue in and around the wound during the healing phase.

Without adequate L-arginine (and subsequently, nitric oxide) available to vascular endothelial cells, arteries may not optimally dilate, which can result in less than optimal blood flow to the organs and extremities.

L-arginine is absorbed and metabolized by the body very quickly, which usually necessitates taking it frequently throughout the day. Sustained-release Perfusia-SR, however, maintains an optimal level of L-arginine over 24 hours with suggested twice-daily use.

Studies on Perfusia-SR show increased blood flow to the heart muscle and the extremities, maintenance of already normal blood pressure, and improved vascular elasticity. A recent study demonstrated improvements in blood flow after Perfusia-SR supplementation in individuals with less than optimum heart health. In another study, Perfusia-SR was given to 29 healthy volunteers for one week and significant support of their already normal cardiovascular health was observed.

Suggested Use

Take 2 capsules two times daily or as recommended by your health-care practitioner.

Other Ingredients

High and low viscosity hydroxypropyl methyl-cellulose and MagnesiumCitrateLaurate (Time-Sorb†), hypromellose (derived from cellulose) capsule, leucine, silicon dioxide.


Tamper Evident: Use only if bottle is sealed.

If pregnant, consult your health-care practitioner before using this product.

Store tightly sealed in cool, dry place.

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Supplement Facts
Serving Size: Two Capsules
Servings Per Container: 60
Two Capsules Contain: Amount Per Serving % DV
L-Arginine† 1 g *
*Daily Value (DV) not established.
†L-Arginine complexed with Time-Sorb, a time-release matrix.

iHerb Customer Reviews

5 Stars
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1 Stars


Posted by Reviewer2719099 on Apr 23, 2011

I read one review how it helped with leg pain,I tried it and it really helps, I do not need pain medication. Thanks to who gave the review.

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6 people found the following review helpful

Used with LCitruline in the past 15-20 days has lowered my ....

Posted by Reviewer1645012 on Aug 15, 2011

as high as 190/90 bp to the 120/65 range. Several times I got 113-115/62-65 range. I LIKE this stuff!!!

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6 people found the following review helpful

great for Raynauds

Posted by Reviewer2650896 on Apr 22, 2011

I have Raynauds and these are great l'arginine for my circulation.I tried cheaper ones but they didn't work like Perfussia!

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5 people found the following review helpful

Natural Blood Thinner

Posted by Reviewer2703003 on Sep 09, 2010

My use of this product is to maintain my blood, and because it is a natural product. I have used Perfusia for many years and found it very good, I will never stop using it

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5 people found the following review helpful

L- Arginine Sensitive

Posted by Reviewer1476045 on Mar 01, 2011

Thorne Research has great products but as with any supplement, everyone reacts differently. I gave 1 star not because of the quality of the product, but because of my body's reaction to taking it. Unfortunately, I guess I am sensitive to L-Arginine beacuse after taking only 1 capsule (recommended dose is 2 capsules), the next day I ended up with cold sore blisters on my cheek. For anyone who has had cold sores on their lips or face, I wouldn't recommend this.

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5 people found the following review helpful

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