Thorne Research, Perfusia-SR, 120 Veggie Caps
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- Dietary Supplement
Sustained-release L-arginine supports cardiovascular function, wound healing, and immune function – and is a biological precursor to nitric oxide.
L-arginine is a semi-essential amino acid involved in multiple areas of human physiology and metabolism. L-arginine significantly affects endocrine function and helps regulate the release of neurotransmitter chemicals, insulin, glucagon (which has the opposite effect of insulin; i.e., it raises blood sugar), and growth hormone. However, one of L-arginine's most compelling contributions to human physiology is its role as a biological precursor of nitric oxide. The vascular endothelium (lining of the arteries) creates nitric oxide from L-arginine, resulting primarily in blood vessel relaxation. This property is critical to maintaining good vascular health, heart health, reproductive health, and protection against oxidative damage.
Maintaining the natural, healthy functions of the vascular endothelium is dependent upon an adequate supply of L-arginine being available to these cells. As mentioned above, the conversion of L-arginine to nitric oxide is responsible for these functions by making the endothelial cells more resistant to oxidative damage and adhesion by otherwise harmful substances. Numerous studies have demonstrated that individuals with sufficient nitric oxide production by endothelial cells have the best opportunity to maintain already normal cardiovascular health.
In a large, double-blind trial that observed male reproductive health issues, 1.6 g L-arginine daily for six weeks resulted in improvement in reproductive health in those men with low nitric oxide metabolism.
Like most amino acids, L-arginine functions as a building block of proteins; however, its presence also appears to support wound healing. Numerous studies show L-arginine supplementation benefits wound healing time and strength of the tissue in and around the wound during the healing phase.
Without adequate L-arginine (and subsequently, nitric oxide) available to vascular endothelial cells, arteries may not optimally dilate, which can result in less than optimal blood flow to the organs and extremities.
L-arginine is absorbed and metabolized by the body very quickly, which usually necessitates taking it frequently throughout the day. Sustained-release Perfusia-SR, however, maintains an optimal level of L-arginine over 24 hours with suggested twice-daily use.
Studies on Perfusia-SR show increased blood flow to the heart muscle and the extremities, maintenance of already normal blood pressure, and improved vascular elasticity. A recent study demonstrated improvements in blood flow after Perfusia-SR supplementation in individuals with less than optimum heart health. In another study, Perfusia-SR was given to 29 healthy volunteers for one week and significant support of their already normal cardiovascular health was observed.
Take 2 capsules two times daily or as recommended by your health-care practitioner.
High and low viscosity hydroxypropyl methyl-cellulose and MagnesiumCitrateLaurate (Time-Sorb†), hypromellose (derived from cellulose) capsule, leucine, silicon dioxide.
Tamper Evident: Use only if bottle is sealed.
If pregnant, consult your health-care practitioner before using this product.
Store tightly sealed in cool, dry place.
|Serving Size: Two Capsules|
|Servings Per Container: 60|
|Two Capsules Contain:||Amount Per Serving||% DV|
|*Daily Value (DV) not established.
†L-Arginine complexed with Time-Sorb, a time-release matrix.
I have Raynauds and these are great l'arginine for my circulation.I tried cheaper ones but they didn't work like Perfussia!
I read one review how it helped with leg pain,I tried it and it really helps, I do not need pain medication. Thanks to who gave the review.
Posted by 5625779604803800296 on May 03, 2016
Having undertaken readings into the research of the studies that have been done with Perfusia SR, I decided to try some. Along with other supplements there seems to be merit in the belief that it is good for the arteries and "Blood Pressure". I have found that it has contributed to lowering blood pressure for a family member. So it is definitely worth trying.
Helping my husband with a bad heart
Posted by Rena61 on Jun 12, 2015
We are giving this a try, so far it seems to be helping with his mis-beats. He is not having them as frequently. Time will tell though.
Could be quite helpful depending on what your blood pressure is. In a book in which I read about this supplement, the author states that pre-hypertension and low to low-medium hypertension blood pressure will most likely see different results. I mention the book below, and I do give this product a t
Posted by Reviewer1549502 on Apr 12, 2013
Although this supplement could help blood pressure, I find it a bit expensive due to the sustained released formulation, but this formulation sounds like an important factor for this amino acid. I suggest reading the following book which I first ordered that talks abouts different supplements like this one, and much more information. Even if you must take blood pressure medication, supplements such as this one may have long term health benefits for the cardiovascular system, and may keep the need for more blood pressure medication at bay. Healthy Origins, The Blood Pressure Cure, Robert E. Kowalski, 306 Page Paperback Book
Posted by SRicketts on Mar 27, 2013
Have had my husband on this product for several months now. Hoping to improve his blood pressure but haven't had it taken lately.