Doctor's Best, SAM-e (S-Adenosyl-L-Methionine) (S-Adenosyl-L-Methionine) 200, 60 Enteric Coated Tablets
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- Science-Based Nutrition
- Pharmaceutical Grade
- Dietary Supplement With 200 mg Active S-Adenosyl Methionine Per Tablet
- Enhances Mood & Neural Function
- Promotes Joint Comfort & Mobility
- Supports Liver Health & Detoxification
- Sealed in Blister Packs for Freshness & Convenience
S-Adenosyl Methionine (SAMe) is derived from the amino acid methionine and is one of the most important methyl donors in the central nervous system. Methylation (donation of methyl groups) is an essential process in ensuring the proper function of a number of organ systems. SAMe is involved in numerous biochemical reactions in tissues including the liver, joints and brain. SAMe is also required for the biosynthesis of critical neurotransmitters and hormones.
Supplementing with SAMe
The manufacturing process of SAMe yields two forms, the S,S and the R,S isomers. The S,S isomer is the active form that mediates biochemical activity in the human body, whereas the R,S form is considered to be biologically inactive. The Italian SAMe used in our SAMe 200 is processed to yield the highest available percentage of the active pure S,S form on the market.
SAMe and Joint Function
SAMe may enhance cartilage protection and promote the synthesis of proteoglycans, essential components of connective tissue. Clinical studies show an ability of SAMe to enhance mobility and movement, and promote joint comfort.
SAMe and Neural Health
SAMe-catalyzed methylation reactions promote the synthesis of neurotransmitters, which have the potential to promote enhanced mood. SAMe may also upregulate the production of phosphatidylcholine, supporting cognitive function.
SAMe and Liver Function
SAMe enhances liver synthesis of glutathione, an antioxidant. Glutathione promotes detoxification and liver protection. Studies show SAMe may protect liver tissue from injury caused by a number of toxins.
Our SAMe 200 contains 200 mg of active SAMe in each tablet. Doctor's Best utilizes only the highest quality Italian SAMe available on the market. This ensures that you receive the most potent SAMe product with the highest percentage of the active S,S form per serving, bar none.
Adult Use: Take 1 tablet daily away from food, or as directed by a health care professional. Do not chew or crush tablet.
Cellulose gel, methacrylic acid copolymer, compritol 888ATO, talc, triethyl citrate, titanium dioxide, magnesium stearate, mannitol, glycerol palmitostearate, silica, medium chain triglycerides, sodium starch glycolate and iron oxide.
The SAMe found in Doctor's Best SAMe 200 mg is free from yeast, dairy, gluten, soy, wheat, and artificial flavoring.
Contains nothing other than listed ingredients.
Individuals using antidepressant medications should consult with their prescribing physician prior to using this product. Individuals diagnosed with bipolar disease or manic depression should avoid supplementing with SAMe. Do not use if pregnant or nursing. May cause gastrointestinal discomfort in a small percentage of people.
SAMe 200 is sealed in blister packs for freshness and stability.
Store product in a cool, dry place to ensure maximum quality.
|Serving Size: 1 tablet|
|Servings Per Container: 60 servings|
|Amount per serving||% Daily Value|
|S-Adenosyl Methionine (from 400 mg of SAM-e tosylate disulfate)||200 mg||†|
|† Daily Value not established.|
iHerb Customer Reviews
Ordered this product for moodiness and slight depression. I thought it would take some time for it to work, but right after I took the first one, instead of getting ready for my date with my friend, I went upstairs and lied down and stared at the ceiling for at least 30 minutes. I remained at taking one capsule a day and continued to feel dopey and spaced out. At work I tripped at least two times and couldn't focus on what I was doing. On the weekend I had to take a nap in the afternoon and didn't wake up until 9pm. I think I would consider taking this again for my first day of my periods or for severe pms, but I can't take this and work. It feels like I'm on a recreational drug or something. It works right away so keep that in mind; and also it did improve my mood. Found myself having the urge to sing and dance for no specific reason.
One of the most important parts of the methylation cycle for helping depression. Must have ! Noticed differnace in 10 days.
Posted by 5491289351029564181 on May 03, 2016
400 works better
Posted by 5082787541542153073 on May 02, 2016
Remember that scene in Limitless when the main character, Eddie, takes the pill for the first time? Well nothing's that good but this comes pretty close!
Posted by Jovana on Dec 16, 2015
Doesnt work for my anxiety. like i dont take anything, this is bad product for anxiety !
Be careful coming off this!
Posted by 5419999165713806075 on Jul 18, 2015
If you are taking this regularly and decide to come off it, reduce it very gradually. I had very strange bodily symptoms when I stopped abruptly. Personally I would not use SAMe in any form again.