I decided to try this for irritable bowel. I took the loading dose for 5 days as suggested. After day 2, I had some stomach cramps and I was gassy but I continued using the product. After day 4, the cramps and gassiness subsided. I am now 3 days into the regular dosing (1 in the AM, 1 in the PM). So far so good but it is too early to tell if it is doing anything. I wrote the review now in case anyone tries this and has gas or cramps. It seems to subside after several days usage.