I have been taking Estrovera for two weeks. I noticed improvements the first day. Since my hyterectomy, normal activities were becoming unbearable. My hot flashes were very frequent, during the day working outside was rediculous. I was dressed for winter one minute, then down to indoor clothes the next. I awoke so much at night I was tired all the time and I couldn't think straight. I am still having hot flashes, but the frequency is much less. I average waking 3 times a night now instead of every 45 mins to an hour. I HIGHLY recommend this product.