This product causes severe headaches for me beginning a few hours after I take it and increasing for about 24 hours. At that point, it's almost equal to a migraine and accompanied by nausea. When I ordered the 50 mg. capsules, I thought I was getting a fairly low dosage, since they range from 10-150 mg., but after reading current literature, I've learned that it's now recommended to not take more than 10 mg./day maximum, and most people should start much lower than that: 2.5 mg./day. Also, it should not be taken every day, but users should develop a program of, for example, taking it for 5 days then going without for 2-5 days. I'm delighted to have figured out the source of these blinding headaches, but not so sure about using pregnenolone, even at a low dose. I have no idea if it's effective, because I've been so sick the day after taking it, "increased energy" is hardly a result I'd notice.

My large-breed senior dog has spondylosis in her lower spine, which causes inflammation and severe pain at times. For months we struggled with giving her powerful Rx drugs to relieve it (I hate using those, but when she was in so much pain she could barely walk, I would break down and give her Rimadyl and Tramadol; it took both to make her comfortable). Learned about curcumin a few weeks after I'd injured my knee; I began taking it and giving it to her, too. The inflammation in my knee improved quickly, but more importantly, my girl is mostly pain free now. She gets 2 capsules a day, and is in less pain than she's been in for years. No side effects, and even when she plays too hard with other dogs, I just give her an extra capsule, and she exhibits no more than a little stiffness the following day.

I no longer use toothpaste, and usually use baking soda and/or sea salt. I like this powder mostly because of the delightful "zing" created by the magnesium, so I'll use it occasionally as a treat. It is difficult to keep the powder confined to the toothbrush, because the puff of air expelled from the bottle tends to blow it around. I've learned to cup the head of the brush in my palm to catch the powder that is inevitably knocked off of the bristles.

Some of these reviews make me wonder if I'm using the same product (which I am). This floss begins fraying as soon as I insert it between two teeth. Even when I use about two feet of it so that it is constantly shifted, it is still completely frayed by the time I finish flossing. Incredibly frustrating, especially since it leaves so many fibers between my teeth . . . which I then have to try to floss out. I had also hoped that the tea tree oil would be refreshing, but I can't tell that there's anything on this floss. Very glad I got it as a free sample, because I will certainly never buy the product.