I have had bladder issues for many years now... I just couldn't 'hold it'... I was on bladder control medicine for years. But then I saw a new urologist and he suggested D-Mannose and weened me off Enablex. I can't believe it actually worked... I've been sleeping through the night and can make an hour drive without stopping to pee! I started out ordering D-Mannose from the doctors website which was a whopping $70 for a month and a half supply. I was skeptical trying this 'less-expensive' brand but I'm so glad I did it works just as good if not better and for less then half the price! yay!