My mother turned 50 and was diagnosed with Hypothyroid, most women do at this age. She absolutley refused to take Synthroid, she just hates pills. So I talked her into taking the supplement instead. She has been taking two pills every morning for the past three months & she says that she feels much better. She does not feel as lethargic & tired as she used to. I'm a nurse myslef, I felt a little sceptic about it at first. But since I have such strong history of Hypothyroid, I'm willing to give it a try. So I came back to order some more.