I have been suffering for five months with clostridium difficule, and have taken antibiotics from my doctor a couple of times, but the diarrhea would come back. I did some research on the internet and found that Saccharomyces Boulardii could help with this condition. I started it, and within three weeks it helped a great deal. Last appointment with my doctor I told him what I was taking and he told me that was the very best probiotic I could take for my condition and to keep taking it. I am not completely well, but it is improving a lot. Thanks for the great product. Lola