I purchased this product originally for my husband who has adult acne. He had been taking minocycline over the past several years off and on, and had gained 20 lbs. for no apparent reason. He did not do the recommended loading dose so it took almost 3 weeks for a noticable improvement. He still has breakouts, but not nearly as severe and he has dropped 12 lbs. in the process. Our two teenage sons are also on it now and while they do still have acne, they don't get the huge red bumps anymore. My husband is on his third month and the boys have been on it close to a month now.