This product was recommended by my healthcare practitioner, over another probiotic I was using at the time. I was happy enough with the "pearls" I already used, but I do beleive that on the whole,this product is even more effective. I do not see the point of the Ohhira Professional Formula with this product, and the increased costs associated with it, when this product (12 Plus Original Formula) ingredient listing is essentially the same. A product is either truthful in its claims, and a quality product, or it's not. I hope this has been helpful.