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Life Extension, Mega Benfotiamine, 250 mg, 120 Veggie Caps

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In Stock
  • Expiration Date: Oct 2018
  • Shipping Weight:
    0.28 lbs
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  • Product Code: LEX-92512
  • UPC Code: 737870925125
  • Package Quantity: 120 Veggie Caps
  • Dimensions:
    4.5 x 2.5 x 2.5 in, 0.2 lbs
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Product Overview


  • For Longer Life
  • Fat & Water Soluble Vitamin B1
  • Dietary Supplement

Benfotiamine is the fat soluble form of vitamin B1 clinically tested to offer protection against advanced glycation end products, typically associated with blood glucose irregularities.

Mega Benfotiamine

Benfotiamine, a fat-soluble form of vitamin B1 (thiamine), supports healthy blood sugar metabolism and helps protect the body’s tissues against advanced glycation end products and oxidative stress.66 For example, the enzyme transketolase is critical to blood sugar metabolism. Like many enzymes, transketolase requires a co-factor. In this case, it needs assistance from thiamine. Unfortunately, thiamine is water-soluble, which makes it less available to the interior of the cell. Benfotiamine is fat-soluble and can easily penetrate into the inside of cells. It is also more bioavailable than the water-soluble thiamine.

In a landmark study, benfotiamine effectively increased transketolase activity in cell cultures by an astounding 300%, compared to a mere 20% for thiamine. This robust activation was sufficient to block three of the four major metabolic pathways leading to blood vessel damage. Benfotiamine also blocks the activation of the transcription factor known as nuclear factor-kappa B (NF-kB), which is implicated in numerous inflammatory conditions.

Overall, benfotiamine can activate glucose metabolism and promote healthy blood glucose levels in those already within normal range. Benfotiamine also helps maintain healthy endothelial function and supports the health of the nerves, kidneys, eyes, blood vessels, and heart.

Suggested Use

Read the entire label and follow the directions carefully prior to use.

Take one (1) to four (4) capsule(s) daily with or without food, or as recommended by a healthcare practitioner.

Other Ingredients

Vegetable cellulose (capsule), microcrystalline cellulose, dicalcium phosphate, rice flour, vegetable stearate, silica.

Contains rice.

This product contains NO milk, egg, fish, peanuts, crustacean shellfish (lobster, crab, shrimp), soybeans, tree nuts, wheat, yeast, gluten, or corn. Contains NO sugar, and no artificial sweeteners, flavors, colors, or preservatives.


  • Keep out of reach of children.
  • Do not exceed recommended dose.
  • Do not purchase if outer seal is broken or damaged.
  • When using nutritional supplements, please consult your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.

Store tightly closed in a cool, dry place.

Supplement Facts
Serving Size: 1 Vegetarian Capsule
  Amount Per Serving % Daily Value
Thiamine (vitamin B1) (as thiamin HCl) 10 mg 667%
Benfotiamine 250 mg **
**Daily Value not established.
iHerb Customer Reviews

great for blood pressure

Posted by Reviewer1587782 on Jan 05, 2017

I use this 2x a day to keep blood pressure in check

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Posted by 4940441607238706589 on Nov 30, 2016

Very Nice produkt

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Ashame dicalcium phosphate is included

Posted by Reviewer3325005 on Jun 17, 2015

Excerpt on Dicalcium phosphate from Livestrong's website: According to evidence gathered by the National Library of Medication, National Institutes of Health, while calcium supplementation is often well-tolerated, high levels could upset the gastrointestinal system. Symptoms of gastrointestinal problems caused by dicalcium phosphate include nausea, vomiting, loss of appetite, constipation, stomach pain, thirst, dry mouth and increased urination. I'd continue buying this product if it weren't for the inclusion of the above ingredient. Defeats the purpose - adding harmful ingredients to a health product!

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Great product, great price!!!!!!!!!!

Posted by Reviewer3131963 on Nov 23, 2014

It is a powerful antioxidant.

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helps with Reynaud's but can raise dopamine

Posted by KentuckyWildcat on May 21, 2014

I started taking this to help with Reynaud's. I started slowly (1 every few days) then graduated to 2 a day. My hands and feet felt warmer almost immediately. I could go outside in 30 degree weather without gloves (absolutely unheard of for me)! Then it appeared that perhaps taking it daily was too much, because I started having slight tachycardia. I researched it and benfotiamine is known to raise dopamine levels which affects heart rate. I stopped taking it and the tachycardia went away. So I will use this in the winter but take it sparingly (maybe 1 a day or 1 every other day would work better).

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