Thorne Research, Methyl-Guard Plus, 90 Veggie Caps
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- Dietary Supplement
- More Concentrated Methylation Support
- Contains Higher Amounts of 5MTHF (Active Folate), B6, B12
- Riboflavin 5'-Phosphate Added for Extra Homocysteine Metabolism Support
- Easy 3 Capsules Daily Dosing
Methylation – the addition of a methyl group (CH4 – one carbon attached to three hydrogens) to another molecule – is an essential and vital biochemical process within the human body that is involved in a large number of biochemical pathways involving neurotransmitters, detoxification, cardiovascular health, eye health, muscle health, bone health, and redox balance. A number of specific nutrients are necessary for methylation to occur normally.
Methyl-Guard Plus contains higher amounts of 5MTHF (the active form of folate), pyridoxal 5'-phosphate (active B6), and methylcobalamin (active B12), than our original Methyl-Guard. We have also added riboflavin 5'-phosphate (the active form of vitamin B2) for its positive effect on homocysteine metabolism and methylation. These ingredients provide the necessary nutrients the body uses to push forward the process of methylation. Methyl-Guard Plus is more concentrated, so your patients will appreciate the recommended daily amount of three capsules, which will improve compliance. Our original Methyl-Guard is still available.
Take 1-3 capsules daily or as recommended by a health-care practitioner.
Hypromellose (derived from cellulose) capsule, calcium citrate, calcium laurate.
Tamper evident: Use only if bottle is sealed.
If pregnant, consult your health-care practitioner before using this product.
Store tightly sealed in a cool, dry place.
|Serving Size: Three Capsules|
|Servings Per Container: 30|
|Three Capsules Contain:||Amount Per Serving||%Daily Value|
|Riboflavin (as Riboflavin 5'-Phosphate Sodium)||90 mg||5,295%|
|Vitamin B6 (as Pyridoxal 5'-Phosphate)||45 mg||2,250%|
|Folate (as L-5-Methyltetrahydrofolate from L-5-Methyltetrahydrofolic Acid, Glucosamine Salt)||3 mg||750%|
|Vitamin B12 (as Methylcobalamin)||3 mg||50,000%|
|Betaine Anhydrous (Trimethylglycine)||1.8 g||*|
|*Daily Value (DV) not established.|
iHerb Customer Reviews
I am taking this supplement along with others to help with methylation and reduce homocysteine. My homocysteine blood tests have improved from 13.7 down to 6.1 (optimum range) but I also used L-Serine (the Amino Acid NOT Phosphatidyl Serine) This supplement contains the L-5-Methyltetrahydrofolate (5MTHF) form of Folate which I can take I DO NOT TAKE FOLIC ACID as I have the C677T Methyl Folate Reductase enzyme genetic mutation (MTHFR) Due to this mutation the folate cycle is impaired in my metabolism so folic acid does not convert to 5-Metyl-tetra-hydro-folate (5MTHF)
If you have discovered you have the MTHFR gene you probable are becoming aware you can't - read CANNOT - process 'normal' folic acid supplements, in fact too much of 'normal' ones can cause you grief - do don't do it!!! This blend is great and even if you don't notice a huge surge in your energy or overall health be assured your body NEEDS folic acid and you will be preventing a multitude of health problems by taking it
Posted by 5472773624811810040 on Apr 07, 2016
esp if you have an activated MTHFr gene mutation
Posted by Reviewer1065582 on Apr 04, 2016
Excellent supplement for people with Methylation Pathway issues. I take two every day.
Life Changing.... Plus
Posted by teresafesta on Feb 02, 2016
After taking Methyl-Guard firstly and weaning my body onto them slowly as I see other people have suggested based on their experiences, After 8-9 months I have opted for the Methyl-Guard Plus so 1/ I didn't need to take as many (as they are higher potency) 2/ Added B5 benefit and I am once again a happy girl. I am feeling better within myself (took about a month though) life can still be stressful but I cope better now & my stomach issues are no where near as bad (avoid folic acid by reading ingredient labels as its added to a lot of stuff these days - mostly wheat products) Also it has helped balance my hormone levels as my pre-menstrual symptoms have eased also as a result of the B6. Win Win for Me. Love the Methyl-Guard Plus Product. Thank You Thorne Research !!!
Thorne Methyl-Guard Plus, 90 veggie caps
Posted by 4875278073496497107 on Dec 23, 2015
Good for MTHFR
Posted by 5535909113594041132 on Sep 13, 2015
This was a bit strong for me (I am only 50kg and could do with lesser amounts). You need to adjust your dosage individually. I might prefer to take my B12 sublingually too in both methyl and adenosyl forms (good for fatigue issues), so don't have to worry about any stomach absorption issues as it goes straight into blood. I am also trialing taking methylfolate as chewable tablet.