An avid health researcher and seeker for a decade I feel strongly that value for money is an important issue. Brands that I recommend highly are Thorne Research, Jarrow, Doctor's best and Now. Metylation support and detox support are my main health strategies, thus my choice of supplements. ~ primum non nocere ~
Brand is top notch IMO, supplement can be helpful if you tolerate and dosage appropriately. A lot of people will have severe detox reactions to this if sensitive to sulfur. Many people (i.e. CFS/ME sufferers) are inefficient at metabolizing sulfur compounds and the loose sulfur in this can end up as sulfates and sulfites. I tried a similar but swedish brand of MSM in '07, got hypothyroid and chilly for many weeks and months thereafter. Resolved when I upped the molybdenum and understood importance of methylation and transsulfuration in detoxing. For people having adverse reactions to this, it can be helpful to have in mind that the product is not stale or bad, but it might not suit your unique detox profile. If you include it in your regime, you may benefit from some extra vitamin C, Molybdenum and possibly a B - Complex (with high Thiamine, since sulfites deplete this vitamin)
Certainly feel the effect of Selenomethionine. It creates calmness and also helps with sleep. Having sub-optimal thyroid for a long period, this is something I take every day. Some formulations out there also equips their selenium with riboflavin. I take this aside and I believe IMO that others should complement their selenium with a b complex. Professor Gerhard Schrauzer of San Diego has dedicated much of his career to this micro-nutrient, formerly thought of as poisonous. He states that it offers a lot of anticarcinogenic potential. The late and great Abram Hoffer spoke warmly about Selenium. Price range of this brand's product line is always very reasonable IMHO.
Posted by philla on Jan 01, 2014 | Verified Purchase
Biofilms are emerging as something that have to be adressed in stubborn lyme infections. Heavy metals, acidosis and other perils of modern civilization are said to be exacerbating this tiny tick borne infection. The Washington state based eminent doctor Klinghardt uses enzymes (serrapeptase, nattokinase, etc) as therapeutic means to break down these slimy bacterial colonies. Maybe also a goot shot for persistent candidiasis.. I bought this with the mere intention to ameliorate my recurring digestive issues. I was very happy with the effect it had on my tummy.
Copper is a mineral that far too often is overloaded in diets and environment these days. In people with adrenal fatigue and MTHFR related health issues (often heavy metal burden..) copper can turn 'biounavailable' in the body. Also copper should be balanced with Zinc (which is far more sparse in diet), and as the ratio between those minerals get skewed towards high Cu, a share of health issues can develop (e.g. hormonal imbalances, estrogen dominance, etc). Molybdenum can help you maintain a correct ratio between the two important minerals. Cancer needs Cu for growth of blood vaults (angiogenesis) and some experimental research has suggested Molybdenum could have a place in cancer therapy by starving the cancer of its needed copper. Amy Yasko, a front figure and hero in the world of treating and reversing autism in children, points out that Molybdenum could help to detoxify ammonia (nitrogen waste) and sulfites (toxic end product of sulfur). Personally I use this mineral with Zinc (30 -40 mg) and it helps resolve some of my 'wired but tired' issues so often common to people with chronic fatigue issues. Also feel an effect on sound sleep.
I am compund heterozygous MTHFR (677 and 1298) and this supplement substitutes for food based folate. Great product, brand and dosage. I believe some people open the capsule and sublingually absorb the powder, but capsules seem fine for me, as it is less binders, fillers, etc.
I have recurring issues wih gut dysbiosis so this is certainly a keeper in my stack. Affordable as always from NOW. Buying a similar product in Norway would cost me over 50 $ (!)
High dose Niacin is therapeutically perpetuated through the work of Abram Hoffer and Carl Pfeiffer, some of the pioneers of ortho-molecular medicine. It acts on many levels in the body, forming coenzyme NADH and facilitating the breakdown of food for ATP/energy. Also recommended for maintaining good HDL/LDL cholesterol level ratios in blood. I was happy with this product, but since I use Niacin in lesser quantities, I will buy their Niacin 500 mg next time. Also, beware that this should be balanced with other B - vits, and since Niacin acts as a Methyl Acceptor (in contrast to -donor), it could be recommended to up your vitamin B6, Folate and b12 to avoid too much methyl draining. Horse pill size caps BTW :)
Posted by philla on Nov 04, 2009 | Verified Purchase
Good value for money but the supplement would have been better if they had excluded the Magnesium Oxide which acts like a laxative.. I get loose stools if I take 3-4 of those a day.
Lecithin provides the body with choline, a very important precursor to phosphatidylcholine (cell membrane fluidity) and acetylcholine (important neurotransmitter for muscles and cognitive function.) This is a bottle that will last for a while, thus it is very budget friendly, and top notch quality. A pinch of this in your morning smoothie or porridge du jour is a very good way to get going. Possible inclusions: hemp seeds, vegetable source EFA:DHA:GLA oil.
Since I take individual nutrients and tailor them gently and precisely, I am not a fan of multi-min's. However, I bought this regularly for almost two years and they are very cleverly formulated. All the right coenzymated B-vits, trace elements (with the omission of Fe and Cu) and six caps as a full label dosage. This way you could increase or decrease dosage to individual needs. I usually prefere Thorne when I can afford it.