Posted by iHerb Customer on Jan 16, 2013 | Verified Purchase
I had been trying desperately to lower my homocysteine with a high dose of ordinary folate. It had worked in 2004, but not any more. Then I read about 5-MTHF and thought that 1 mg should do it. Disappointment again. Then I made a mistake and ordered 5-MTHF in the 5 mg strength. That did it. My number is 8.5 where I want it to be. I may have to toggle back and forth between the two strengths because it can be unwise to lower homocysteine too much.