Added to Cart
Total:
Discount:
Together:
Quantity:
Cart Total:
Checkout
Customers Also Bought:
24/7 Help

Doctor's Best, SAM-e, 400 mg , Double-Strength, 30 Enteric Coated Tablets

$19.57

Thank you!

Your email is being processed.

Doctor's Best, SAM-e, 400 mg , Double-Strength, 30 Enteric Coated Tablets

Click to zoom
Shipping Saver ?
MSRP:
$39.99
Our Price:
$19.57
You Save:
$20.42 (51)
  • Quantity Discount
  • Buy 3+
    Save 5%
Quantity:
Quantity Discount:
Buy 3+
$18.59
(5% off)

Sorry, this product is no longer in stock.

Earn 5% Loyalty Credit ?

Doctor's Best, SAM-e, 400 mg , Double-Strength, 30 Enteric Coated Tablets

In Stock
400 mg
400 mg
$19.57
200 mg
--
30 Tablets
30 Tablets
$19.57
60 Tablets
$40.39
  • Expiration Date: 03/2020
  • Shipping Weight:
    0.27 lbs
    Switch to Metric units
  • Product Code: DRB-00151
  • UPC Code: 753950001510
  • Package Quantity: 30 Tablets
  • Dimensions:
    1.8 x 3.3 x 6.3 in, 0.15 lbs
    Switch to Metric units
Product Overview

Description

  • Science-Based Nutrition
  • Enhanced Mood and Neural Function
  • Promotes Joint Comfort and Mobility
  • Supports Liver Health and Detoxification
  • Vegan
  • Dietary Supplement
  • Gluten Free - Soy Free - Vegan

SAM-e (S-Adenosyl Methionine) is derived from the amino acids methionine and ATP (Adenosine Triphosphate). ATP is normally synthesized in the body but may become depleted from sickness and aging. SAM-e is concentrated in the liver and brain and has multiple mechanisms of action in the body. As a major methyl donor, it synthesizes hormones, nucleic acids, proteins, phospholipids, catecholamines, and other neurotransmitters.

Supplementing with SAM-e

The manufacturing process of SAM-e yields two forms, the S,S and the R,S isomers. The S,S isomer is the active form the mediates biochemical- activity in the human body, whereas the R,S for is considered to be biologically inactive. The Italian SAM-e used in our SAM-e 400 is processed to yield the highest available percentage of the active pure S,S form on the market.

SAM-e and Joint Function

In clinical trials, SAM-e has been shown to help reduce pain in joints and increase joint comfort and mobility by promoting the synthesis of proteoglycans, essential components of connective tissue.

SAM-e and Mood and Cognitive Function

SAM-e's ability to boost brain cell methylation facilitates youthful DNA enzymatic actions which may help account for its mood-elevating properties. These enzymatic actions are required for the healthy conversion of neurotransmitters, such a serotonin and dopamine. SAM-e also facilitates glutathione usage which improves the body's antioxidant defense and it helps maintain acetylcholine levels necessary for cognitive function.

SAM-e and Liver Function

In order to perform its detoxification role, SAME-e facilitates healthy methylation enzymatic processes and boost hepatic levels of glutathione, a critical antioxidant which helps protect against free radicals. SAME-e acts as a methyl donor in the synthesis an formation of phosphatidylcholine and L-cysteine, both necessary for maintaining liver health.

Our Double Strength SAM-e 400 contains 400 mg of active SAM-e in each tablet. Doctor's Best utilizes only the highest quality Italian SAM-e available on the market. This ensures that you receive the most potent SAM-e product with the highest percentage of the active S,S form per serving.

Suggested Use

Adult Use: Take 1 tablet daily away from food, or as recommended by a nutritionally-informed physician. Do not chew or crush tablet.

Other Ingredients

Cellulose, methacrylic acid copolymer, glyceryl behenate, magnesium silicate, triethyl citrate, titanium dioxide, magnesium stearate, mannitol, glycerol palmitostearate, silicon dioxide, medium chain triglycerides, sodium carboxymethyl starch and iron oxide.

Warnings

Individuals using antidepressant medications should consult with their prescribing physician prior to using this product. Individuals diagnosed with bipolar disease or manic depression should avoid supplementing with SAMe. Do not use if pregnant or nursing. May cause gastrointestinal discomfort in a small percentage of people.

Store in a cool dry place.

Double Strength SAM-e 400 is sealed in blister packs for freshness and stability.

Store product in a cool, dry place to ensure maximum quality.

Supplement Facts
Serving Size: 1 Tablet
Servings Per Container: 30 servings
  Amount Per Serving %Daily Value
S-Adenosyl Methionine
(from SAM-e tosylate disulfate)
400 mg
† Daily Value not established.
iHerb Customer Reviews
 

SAM-e

Posted by iHerb Customer on Dec 12, 2017 | Verified Purchase

SAM-e and TMG are this power couple that keep depression away. Aids the methylation cycle

Thanks for your feedback!

WORKS!!!i highly recommend to put the C0'DE: "TA L65 41" for 5 % Any Order!* ( no spa ces)*

Posted by iHerb Customer on Dec 10, 2017 | Verified Purchase

This works just perfect for me! I feel much better with it! I highly recommend putting the c~0 '~d~e "TA L65 41" for 5% AnyOrder!* ( no spa ces)*

Thanks for your feedback!

Great

Posted by iHerb Customer on Dec 08, 2017 | Verified Purchase

Really positive effect on mood and energy. Loved it!

Thanks for your feedback!

Great product

Posted by iHerb Customer on Dec 04, 2017 | Verified Purchase

This product worked within a week. I have been on it about one year now and my anxiety has gone down significantly. This anxiety lead to depressed state which has now lifted too. Highly recommend it. A little expensive but Iherb has the cheapest I could find, a vegan product too and a good brand.

Thanks for your feedback!

Works Really Well For Mood

Posted by iHerb Customer on Nov 23, 2017 | Verified Purchase

This works instantly. Better than saint johns worth. Makes my day a LOT brighter.

Thanks for your feedback!