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Doctor's Best, SAM-e, 400 mg, Double Strength, 60 Enteric Coated Tablets

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Doctor's Best, SAM-e, 400 mg, Double Strength, 60 Enteric Coated Tablets

In Stock
400 mg
400 mg
$38.66
200 mg
$21.65
60 Tablets
30 Tablets
$19.06
60 Tablets
$38.66
  • Expiration Date: Feb 2019
  • Shipping Weight:
    0.3 lbs
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  • Product Code: DRB-00252
  • UPC Code: 753950002524
  • Package Quantity: 60 Enteric Coated Tablets
  • Dimensions:
    6.3 x 3.3 x 2 in, 0.25 lbs
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Product Overview

Description

  • Science-Based Nutrition
  • Dietary Supplement with 400 mg Active S-Adenosyl Methionine Per Tablet
  • Enhances Mood & Neural Function
  • Promotes Joint Comfort & Mobility
  • Supports Liver Health & Detoxification
  • Pharmaceutical Grade
  • Sealed in Blister Packs for Freshness & Convenience
  • Suitable for Vegetarians

S-Adenosyl Methionine (SAMe) is derived from the amino acid methionine and is one of the most important methyl donors in the central nervous system. Methylation (donation of methyl groups) is an essential process in ensuring the proper function of a number of organ systems. SAMe is involved in numerous biochemical reactions in tissues including the liver, joints and brain. SAMe is also required for the biosynthesis of critical neurotransmitters and hormones.

Supplementing with SAMe

The manufacturing process of SAMe yields two forms, the S,S and the R,S isomers. The S,S isomer is the active form that mediates biochemical activity in the human body, whereas the R,S form is considered to be biologically inactive. The Italian SAMe used in Double-Strength SAMe 400 is processed to yield the highest available percentage of the active pure S,S form on the market.

SAMe and Joint Function

SAMe may enhance cartilage protection and promote the synthesis of proteoglycans, essential components of connective tissue. Clinical studies show an ability of SAMe to enhance mobility and movement, and promote joint comfort.

SAMe and Neural Health

SAMe-catalyzed methylation reactions promote the synthesis of neurotransmitters, which have the potential to promote enhanced mood. SAMe may also upregulate the production of phosphatidylcholine, supporting cognitive function.

SAMe and Liver Function

SAMe enhances liver synthesis of glutathione, an antioxidant. Glutathione promotes detoxification and liver production. Studies show SAMe may protect liver tissue from injury caused by a number of toxins.

Our Double-Strength SAMe 400 contains 400 mg of active SAMe in each tablet. Doctor's Best utilizes only the highest quality Italian SAMe available on the market. This ensures that you receive the most potent SAMe product with the highest percentage of the active S,S form per serving, bar none.

Double Strength SAMe is sealed in blister packs for freshness and stability.

Suggested Use

Adult Use: Take 1 tablet daily away from food, or as recommended by a nutritionally-informed physician. Do not chew or crush tablet.

Other Ingredients

Cellulose, methacrylic acid copolymer, glyceryl behenate, magnesium silicate, triethyl citrate, titanium dioxide, magnesium stearate, mannitol, glycerol palmitostearate, silicon dioxide, medium chain triglycerides, sodium carboxymethyl starch and iron oxide.

The SAMe found in Doctor's Best SAMe 400 mg (Double Strength) is free from yeast, dairy, gluten, soy, wheat and artificial flavoring

Contains nothing other than listed ingredients.

Warnings

Individuals using antidepressant medications should consult with their prescribing physician prior to using this product. Individuals diagnosed with bipolar disease or manic depression should avoid supplementing with SAMe. Do not use if pregnant or nursing. May cause gastrointestinal discomfort in a small percentage of people.

Store product in a cool, dry place to ensure maximum quality.

Supplement Facts
Serving Size: 1 tablet
Servings Per Container: 60 servings
  Amount per serving % Daily Value
S-Adenosyl Methionine (from 800 mg SAM-e tosylate disulfate) 400 mg
† Daily Value not established.
iHerb Customer Reviews
 

Well priced. Hard to get in stores sometimes. Depression wonder stuff!

Posted by iHerb Customer on Aug 14, 2017 | Verified Purchase

I have observed significant benefit from this supplement when used as an adjunct to my anti-depressants. The Dr's Best brand through i=Herb doesn't need refrigeration, which means I can leave it beside my bed and remember to take every morning. This product is also $10-15 cheaper than I've found anywhere in a shop. I've also had occasions where stores are unable to get a regular supply, Most appreciative of this product via i-Herb.

Thanks for your feedback!

SAM-E

Posted by iHerb Customer on Aug 01, 2017 | Verified Purchase

I don't know what this stuff does for me but I've been taking it every day since my doctor told me to take it about 25 years ago. And I have survived to be 77 years old.

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So far so good

Posted by iHerb Customer on Jul 03, 2017 | Verified Purchase

Using it daily. Thanks

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Doctors Best SAM-e

Posted by iHerb Customer on Jun 25, 2017 | Verified Purchase

Been using this for over a year has been helpful in maintaining my immune system

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works for me

Posted by iHerb Customer on Jun 21, 2017 | Verified Purchase

I have arthritis and it does help reducing the pain level, also gives bit more mobility

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