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Thorne Research, Niasafe-600, 180 Veggie Caps

Thorne Research, Niasafe-600, 180 Veggie Caps

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In Stock
  • Expiration Date: Dec 2018
  • Shipping Weight:
    0.47 lbs
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  • Product Code: THR-11402
  • UPC Code: 693749114024
  • Package Quantity: 180 Veggie Caps
  • Dimensions:
    2.8 x 2.8 x 5.2 in, 0.4 lbs
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Save $4.00 when you purchase these items today for only $53.29
Total: $57.29
Combo Discount: - $4.00
Together: $53.29

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Product Overview


  • Dietary Supplement
  • Hypoallergenic
  • Inositol Hexaniacinate - a Safer, Non-Flushing Alternative to Niacin
  • Provides a Higher Amount of Niacin without the Flushing
  • Unlike Time-Release Niacin - Niasafe is Easy on the Liver
  • Supports Peripheral Vascular Circulation
  • Supports Lipid Metabolism

Niacin has long been used to support good cardiovascular health. It has been proven effective at helping to maintain already normal levels of cholesterol.

The side effects of high amounts of niacin that may occur range from flushing and itching to liver toxicity and impaired glucose tolerance. Therefore, the need for a safer approach to niacin supplementation resulted in the investigation of niacin esters. One of the most widely studied niacin esters is inositol hexaniacinate (IHN). In numerous trials IHN has been found to be virtually free of the side effects associated with conventional niacin therapy. Pharmacokinetic studies show the IHN molecule is absorbed intact and slowly hydrolyzed in the bloodstream, releasing free niacin and inositol and having a diminished impact on the liver. Maximum serum levels are reached approximately 10 hours after ingestion, thus allowing for a more delayed release of niacin that reduces the risk of flushing.

A review of the literature reveals numerous positive studies on the use of IHN to support good circulatory health, particularly the support of vascular circulation to the extremities.

Suggested Use

Take 1 capsule one to three times daily or as recommended by your health-care practitioner.

Other Ingredients

Hypromellose (derived from cellulose) capsule, leucine, silicon dioxide.


Tamper Evident: Use only if bottle is sealed.

If pregnant, consult your health-care practitioner before using this product.

Store tightly sealed in a cool, dry place.

Supplement Facts
Serving Size: One Capsule
  Amount Per Serving % DV
Niacin (as Inositol Hexaniacinate†) 540 mg 2,700%
Daily Value (DV)
†Does not cause flushing in many patients.
iHerb Customer Reviews

Expensive but ...

Posted by 5561429496858311858 on Mar 18, 2017 | Verified Purchase

I began using Niasafe around a year and a half ago and since then have tried other less expensive products but have always returned to Niasafe. It's the only only which seems to agree with my system and give me the energy I need so I have continued buying it at iHerb, where it is at least affordable. Thank you iHerb! Pleaqse DO keep it in your product line.

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Can't get out of bed without it

Posted by Reviewer3017834 on Dec 20, 2013 | Verified Purchase

Indispensable for mood, energy and liver function. Highly recommended.

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Don't get any red flushes

Posted by OssieA on Oct 16, 2011 | Verified Purchase

Ordinary niacin gave me red rashes if I didn't eat enough when taking. This Niasafe doesn't do that.

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Posted by Reviewer1630744 on Sep 08, 2011 | Verified Purchase

Wonderful product, have had no problems with it nor reactions from it.

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Posted by Reviewer3325914 on Jun 05, 2011 | Verified Purchase

this is a good product. I didn't get any flushes after taking it, like I have done with other niacin products.

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