Doctor's Best, SAM-e (S-Adenosyl-L-Methionine) 400, Double-Strength, 30 Enteric Coated Tablets
- You earn loyalty credit for every order you place at iHerb!
- Loyalty credit is equal to 5% of the value of your order, excluding shipping charges.
- Your loyalty credit will be applied towards your next order as soon as your current order has shipped.
- Your loyalty credits are valid for up to 60 days from the date of your last purchase.
Expiration Date:Expiration Date
The length of time for the expiration date or "best used before" date depends on the type of product, as well as the brand.
Perishable items (such as flax oils or certain probiotics) generally have shorter expiration dates. Although our warehouse is fully air-conditioned, these more fragile items are put in cold storage (freezer or refrigeration unit) for maximum freshness.
Our receiving department does its best to verify and then enter the correct expiration dates for all incoming products. However, discrepancies do occur from time to time. This being said, the exceptionally high turnover at iHerb ensures that our inventory is among the freshest in the industry.
Shipping Weight:0.27 lbsSwitch to Metric units
- Product Code: DRB-00151
- UPC Code: 753950001510
- Package Quantity: 30 Enteric Coated Tablets
1.8 x 3.3 x 6.3 in, 0.15 lbsSwitch to Metric units
- Science-Based Nutrition
- Dietary Supplement with 400 mg Active S-Adenosyl Methionine Per Tablet
- Enhances Mood & Neural Function
- Promotes Joint Comfort & Mobility
- Supports Liver Health & Detoxification
- Pharmaceutical Grade
- Sealed in Blister Packs for Freshness & Convenience
- Suitable for Vegetarians
S-Adenosyl Methionine (SAMe) is derived from the amino acid methionine and is one of the most important methyl donors in the central nervous system. Methylation (donation of methyl groups) is an essential process in ensuring the proper function of a number of organ systems. SAMe is involved in numerous biochemical reactions in tissues including the liver, joints and brain. SAMe is also required for the biosynthesis of critical neurotransmitters and hormones.
Supplementing with SAMe
The manufacturing process of SAMe yields two forms, the S,S and the R,S isomers. The S,S isomer is the active form that mediates biochemical activity in the human body, whereas the R,S form is considered to be biologically inactive. The Italian SAMe used in Double-Strength SAMe 400 is processed to yield the highest available percentage of the active pure S,S form on the market.
SAMe and Joint Function
SAMe may enhance cartilage protection and promote the synthesis of proteoglycans, essential components of connective tissue. Clinical studies show an ability of SAMe to enhance mobility and movement, and promote joint comfort.
SAMe and Neural Health
SAMe-catalyzed methylation reactions promote the synthesis of neurotransmitters, which have the potential to promote enhanced mood. SAMe may also upregulate the production of phosphatidylcholine, supporting cognitive function.
SAMe and Liver Function
SAMe enhances liver synthesis of glutathione, an antioxidant. Glutathione promotes detoxification and liver protection. Studies show SAMe may protect liver tissue from injury caused by a number of toxins.
Our Double-Strength SAMe 400 contains 400 mg of active SAMe in each tablet. Doctor's Best utilizes only the highest quality Italian SAMe available on the market. This ensures that you receive the most potent SAMe product with the highest percentage of the active S,S form per serving, bar none.
Double-Strength SAMe is sealed in blister packs for freshness and stability.
Adult Use: Take 1 tablet daily away from food, or as recommended by a nutritionally-informed physician. Do not chew or crush tablet.
Cellulose, methacrylic acid copolymer, glyceryl behenate, magnesium silicate, triethyl citrate, titanium dioxide, magnesium stearate, mannitol, glycerol palmitostearate, silicon dioxide, medium chain triglycerides, sodium carboxymethyl starch and iron oxide.
The SAMe found in Doctor's Best SAMe 400 mg (Double Strength) is free from yeast, dairy, gluten, soy, wheat and artificial flavoring.
Contains nothing other than listed ingredients
Individuals using antidepressant medications should consult with their prescribing physician prior to using this product. Individuals diagnosed with bipolar disease or manic depression should avoid supplementing with SAMe. Do not use if pregnant or nursing. May cause gastrointestinal discomfort in a small percentage of people.
Store product in a cool, dry place to ensure maximum quality.
|Serving Size: 1 tablet|
|Servings Per Container: 30 servings|
|Amount per serving||% Daily Value|
|S-Adenosyl Methionine (from 800 mg of SAMe tosylate disulfate)||400 mg||†|
|† Daily Value not established.|
Never Take Sam-e without Vitamins B-complex
Never Take Sam-e without Vitamins B-complex
I have been taking this over a month now. good results untill one day i felt fast heart beat and short breath. did some study and took B-complex. Made my heart back to normal in minutes. once again, this is an excelent product but do not take it without vitamin B-COMPLEX.
This product has great benefit
Posted by 5468601371446777539 on Mar 16, 2017
Love this product so far I believe it is improving my mobility and easing my pain
Posted by 5196220325033105901 on Mar 15, 2017
I so love this product, it is of high quality.
Posted by 5641962193700427791 on Mar 13, 2017
The best buy SAMe product I have ever bought! Each tablet is blister-pack protected from light/moisture which is very important for SAMe since it is unstable and needs protection to keep fresh. They work great! I have ordered a lot of these shipped to Sweden. Shipping has been fast and cheap as well. I take them with "vitacure methyl plus" which I hope iHerb will start selling soon also.
Posted by 5237644045860083305 on Mar 12, 2017