Added to Cart
Total:
Discount:
Together:
Quantity:
Cart Total:
Checkout
Customers Also Bought:
24/7 Help

Doctor's Best, SAM-e, 400 mg , Double-Strength, 30 Enteric Coated Tablets

$19.57 $19.57 (Saved $20.42)

Thank you!

Your email is being processed.

Doctor's Best, SAM-e, 400 mg , Double-Strength, 30 Enteric Coated Tablets

Click to zoom
Shipping Saver ?
MSRP:
$39.99
Our Price:
$19.57
You Save:
$20.42 (51)
  • Quantity Discount
  • Buy 3+
    Save 5%
Quantity:

Sorry, this product is no longer in stock.

Earn 5% Loyalty Credit ?

Doctor's Best, SAM-e, 400 mg , Double-Strength, 30 Enteric Coated Tablets

In Stock
400 mg
400 mg
$19.57
200 mg
--
30 Tablets
30 Tablets
$19.57
60 Tablets
$40.39
  • Expiration Date: 01/2020
  • Shipping Weight:
    0.27 lbs
    Switch to Metric units
  • Product Code: DRB-00151
  • UPC Code: 753950001510
  • Package Quantity: 30 Tablets
  • Dimensions:
    1.8 x 3.3 x 6.3 in, 0.15 lbs
    Switch to Metric units
Product Overview

Description

  • Science-Based Nutrition
  • Enhanced Mood and Neural Function
  • Promotes Joint Comfort and Mobility
  • Supports Liver Health and Detoxification
  • Vegan
  • Dietary Supplement
  • Gluten Free - Soy Free - Vegan

SAM-e (S-Adenosyl Methionine) is derived from the amino acids methionine and ATP (Adenosine Triphosphate). ATP is normally synthesized in the body but may become depleted from sickness and aging. SAM-e is concentrated in the liver and brain and has multiple mechanisms of action in the body. As a major methyl donor, it synthesizes hormones, nucleic acids, proteins, phospholipids, catecholamines, and other neurotransmitters.

Supplementing with SAM-e

The manufacturing process of SAM-e yields two forms, the S,S and the R,S isomers. The S,S isomer is the active form the mediates biochemical- activity in the human body, whereas the R,S for is considered to be biologically inactive. The Italian SAM-e used in our SAM-e 400 is processed to yield the highest available percentage of the active pure S,S form on the market.

SAM-e and Joint Function

In clinical trials, SAM-e has been shown to help reduce pain in joints and increase joint comfort and mobility by promoting the synthesis of proteoglycans, essential components of connective tissue.

SAM-e and Mood and Cognitive Function

SAM-e's ability to boost brain cell methylation facilitates youthful DNA enzymatic actions which may help account for its mood-elevating properties. These enzymatic actions are required for the healthy conversion of neurotransmitters, such a serotonin and dopamine. SAM-e also facilitates glutathione usage which improves the body's antioxidant defense and it helps maintain acetylcholine levels necessary for cognitive function.

SAM-e and Liver Function

In order to perform its detoxification role, SAME-e facilitates healthy methylation enzymatic processes and boost hepatic levels of glutathione, a critical antioxidant which helps protect against free radicals. SAME-e acts as a methyl donor in the synthesis an formation of phosphatidylcholine and L-cysteine, both necessary for maintaining liver health.

Our Double Strength SAM-e 400 contains 400 mg of active SAM-e in each tablet. Doctor's Best utilizes only the highest quality Italian SAM-e available on the market. This ensures that you receive the most potent SAM-e product with the highest percentage of the active S,S form per serving.

Suggested Use

Adult Use: Take 1 tablet daily away from food, or as recommended by a nutritionally-informed physician. Do not chew or crush tablet.

Other Ingredients

Cellulose, methacrylic acid copolymer, glyceryl behenate, magnesium silicate, triethyl citrate, titanium dioxide, magnesium stearate, mannitol, glycerol palmitostearate, silicon dioxide, medium chain triglycerides, sodium carboxymethyl starch and iron oxide.

Warnings

Individuals using antidepressant medications should consult with their prescribing physician prior to using this product. Individuals diagnosed with bipolar disease or manic depression should avoid supplementing with SAMe. Do not use if pregnant or nursing. May cause gastrointestinal discomfort in a small percentage of people.

Store in a cool dry place.

Double Strength SAM-e 400 is sealed in blister packs for freshness and stability.

Store product in a cool, dry place to ensure maximum quality.

Supplement Facts
Serving Size: 1 Tablet
Servings Per Container: 30 servings
  Amount Per Serving %Daily Value
S-Adenosyl Methionine
(from SAM-e tosylate disulfate)
400 mg
† Daily Value not established.
iHerb Customer Reviews
 

Moderate Anxiety And Depression

Posted by iHerb Customer on Oct 24, 2017 | Verified Purchase

I bought this product for my wife who has undergone some personal struggles within the last two years. She would suffer from depression and anxiety sporadically and this got worse over time. She noticed a difference in her mood and General well being within the second week of using the product. Would definitely recommend to those who have similar symptoms.

Thanks for your feedback!

This product is great.

Posted by iHerb Customer on Oct 22, 2017 | Verified Purchase

I've found this product works really well and helps with moodiness.

Thanks for your feedback!

Only thing that worked!!!!

Posted by iHerb Customer on Oct 21, 2017 | Verified Purchase

I love these tablets. Great for those with eating disorders because it enhances your mood so much. It helped me many times on those days that I needed food for comfort. It kept me happy all day every day and I will continue to buy these for as long as I live.

Thanks for your feedback!

Item was not posted

Posted by iHerb Customer on Oct 03, 2017 | Verified Purchase

Item was not ever sent. Very disappointing. I have contacted iherb but they had not even replied. Did not have a good experience at all.

Thanks for your feedback!

Helpful

Posted by iHerb Customer on Sep 11, 2017 | Verified Purchase

I am sure the pain of osteoarthritis is diminished after a month of taking this product. despite our wet and cold weather I have had more mobility and less stiffness.

Thanks for your feedback!