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Doctor's Best, Double-Strength SAM-e, 400 mg , 30 Enteric Coated Tablets

Doctor's Best, Double-Strength SAM-e, 400 mg , 30 Enteric Coated Tablets

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$39.99
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In Stock
  • Expiration Date: Nov 2019
  • Shipping Weight:
    0.27 lbs
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  • Product Code: DRB-00151
  • UPC Code: 753950001510
  • Package Quantity: 30 Enteric Coated Tablets
  • Dimensions:
    1.8 x 3.3 x 6.3 in, 0.15 lbs
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Product Overview

Description

  • Science-Based Nutrition
  • Enhanced Mood and Neural Function
  • Promotes Joint Comfort and Mobility
  • Supports Liver Health and Detoxification
  • Vegan
  • Dietary Supplement
  • Gluten Free - Soy Free - Vegan

SAM-e (S-Adenosyl Methionine) is derived from the amino acids methionine and ATP (Adenosine Triphosphate). ATP is normally synthesized in the body but may become depleted from sickness and aging. SAM-e is concentrated in the liver and brain and has multiple mechanisms of action in the body. As a major methyl donor, it synthesizes hormones, nucleic acids, proteins, phospholipids, catecholamines, and other neurotransmitters.

Supplementing with SAM-e

The manufacturing process of SAM-e yields two forms, the S,S and the R,S isomers. The S,S isomer is the active form the mediates biochemical- activity in the human body, whereas the R,S for is considered to be biologically inactive. The Italian SAM-e used in our SAM-e 400 is processed to yield the highest available percentage of the active pure S,S form on the market.

SAM-e and Joint Function

In clinical trials, SAM-e has been shown to help reduce pain in joints and increase joint comfort and mobility by promoting the synthesis of proteoglycans, essential components of connective tissue.

SAM-e and Mood and Cognitive Function

SAM-e's ability to boost brain cell methylation facilitates youthful DNA enzymatic actions which may help account for its mood-elevating properties. These enzymatic actions are required for the healthy conversion of neurotransmitters, such a serotonin and dopamine. SAM-e also facilitates glutathione usage which improves the body's antioxidant defense and it helps maintain acetylcholine levels necessary for cognitive function.

SAM-e and Liver Function

In order to perform its detoxification role, SAME-e facilitates healthy methylation enzymatic processes and boost hepatic levels of glutathione, a critical antioxidant which helps protect against free radicals. SAME-e acts as a methyl donor in the synthesis an formation of phosphatidylcholine and L-cysteine, both necessary for maintaining liver health.

Our Double Strength SAM-e 400 contains 400 mg of active SAM-e in each tablet. Doctor's Best utilizes only the highest quality Italian SAM-e available on the market. This ensures that you receive the most potent SAM-e product with the highest percentage of the active S,S form per serving.

Suggested Use

Adult Use: Take 1 tablet daily away from food, or as recommended by a nutritionally-informed physician. Do not chew or crush tablet.

Other Ingredients

Cellulose, methacrylic acid copolymer, glyceryl behenate, magnesium silicate, triethyl citrate, titanium dioxide, magnesium stearate, mannitol, glycerol palmitostearate, silicon dioxide, medium chain triglycerides, sodium carboxymethyl starch and iron oxide.

Warnings

Individuals using antidepressant medications should consult with their prescribing physician prior to using this product. Individuals diagnosed with bipolar disease or manic depression should avoid supplementing with SAMe. Do not use if pregnant or nursing. May cause gastrointestinal discomfort in a small percentage of people.

Store in a cool dry place.

Double Strength SAM-e 400 is sealed in blister packs for freshness and stability.

Store product in a cool, dry place to ensure maximum quality.

Supplement Facts
Serving Size: 1 Tablet
Servings Per Container: 30 servings
  Amount Per Serving %Daily Value
S-Adenosyl Methionine
(from SAM-e tosylate disulfate)
400 mg
† Daily Value not established.
iHerb Customer Reviews
 

Not keen on excipients

Posted by 4968135610744644202 on Jun 15, 2017 | Verified Purchase

I know titanium dioxide is used for the enteric coating, but I'm not keen on Doctor's Best SAMe for that reason. I now have my SAMe compounded which is more expensive. Also as recommended by my doctor I take 200 mg twice a day rather than a single dose of 400 mg.

Thanks for your feedback!

good value

Posted by bjreviews on Jun 11, 2017 | Verified Purchase

this was the best value SAM-e I could find

Thanks for your feedback!

not sure if it works

Posted by iHerb Customer on Jun 06, 2017 | Verified Purchase

should be as powder in a shake tablets to small and no effect.

Thanks for your feedback!

GREAT!

Posted by Reviewer2551062 on Jun 01, 2017 | Verified Purchase

I would not be without it! Initially, I ordered this for my liver, but my mood and energy improved as well. I take one first thing in the morning and gets me energy and a feel good mood all day.

Thanks for your feedback!

I really notice the difference

Posted by 5299599273358394573 on Jun 01, 2017 | Verified Purchase

I think this does help me feel better when I'm somewhat depressed. I don't take it regularly just when I feel down for a few days. I also notice it helps me sleep right through.

Thanks for your feedback!