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Doctor's Best, SAM-e, 200 mg, 60 Enteric Coated Tablets

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Doctor's Best, SAM-e, 200 mg, 60 Enteric Coated Tablets

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Doctor's Best, SAM-e, 200 mg, 60 Enteric Coated Tablets

In Stock
200 mg
400 mg
200 mg
60 Tablets
30 Tablets
60 Tablets
  • Expiration Date: March 2020
  • Shipping Weight:
    0.25 lbs
    Switch to Metric units
  • Product Code: DRB-00206
  • UPC Code: 753950002067
  • Package Quantity: 60 Tablets
  • Dimensions:
    6.3 x 3.3 x 1.7 in, 0.15 lbs
    Switch to Metric units
Frequently Purchased Together
Product Overview


  • Science-Based Nutrition
  • Helps Enhance Mood and Neural Function
  • Helps Promote Joint Comfort and Mobility
  • Helps Support Liver Health and Detoxification
  • Dietary Supplement
  • Gluten Free - Soy Free - Vegan

SAM-E (S-Adenosyl Methionine) is naturally produced by your body and helps maintain healthy emotions. Various factors such as diet and aging can cause low levels of SAM-e, leaving you feeling unbalanced and moody. Doctor's Best SAM-e help replenish your SAM-e levels and promote a healthy mood.

Supplementing with SAM-e

Soloesse Italian SAM-e is processed to yield the highest available percentage of the active pure S,S form which helps mediate biochemical activity in the human body.

SAM-e and Mood and Cognitive Function

SAM-e helps facilitate DNA enzymatic actions. These enzymatic actions are required for the health conversion of neurotransmitters responsible for healthy emotions, such as serotonin and dopamine. SAM-e also facilitates glutathione usage which improves the body's antioxidant defense and helps maintain acetylcholine levels necessary for cognitive function.

SAM-e and Joint Function

In clinical trial, SAM-e has been shown to help increase join comfort and mobility by promoting the synthesis of proteoglycans, essential components of connective tissue.

SAM-e and Liver Function

SAM-e helps support healthy levels of glutathione, a critical antioxidant which helps protect against free radicals. SAM-e acts as a methyl donor in the synthesis and formation of phosphatidyl-choline and L-cysteine, both necessary for maintaining liver health.

Our SAM-e 200 contains 200 mg of active Soloesse SAM-e in each tablet. Doctor's Best utilizes only the highest quality Italian Soloesse SAM-e available providing slow and targeted release for improved GI tolerance and absorption. This ensures that you receive the most potent SAM-e product with the highest percentage of the active S,S form per serving.

Suggested Use

Take 1 tablet twice daily between meals, or as recommended by a nutritionally-informed physician. Do not chew or crush tablet.

Other Ingredients

Microcrystalline cellulose, magnesium hydroxide, stearic acid, calcium chloride anhydrous, magnesium stearate, colloidal silica anhydrous, calcium oxide, magnesium silicate, natural food glaze, arginine base, glycerol, sodium alginate.


Individuals using antidepressant medications should consult with their prescribing physician prior to using this product. Individuals diagnosed with bipolar disease or manic depression should avoid supplementing with SAMe. Do not use if pregnant or nursing. May cause gastrointestinal discomfort in a small percentage of people.

Store in a cool dry place.

SAM-e is sealed in blister packs for freshness and stability.


While iHerb strives to ensure the accuracy of its product images and information, some manufacturing changes to packaging and/or ingredients may be pending update on our site. Although items may occasionally ship with alternate packaging, freshness is always guaranteed. We recommend that you read labels, warnings and directions of all products before use and not rely solely on the information provided by iHerb.
Supplement Facts
Serving Size: 1 tablet
Servings Per Container: 60 servings
  Amount Per Serving %Daily Value
S-Adenosyl Methionine (from SAM-e tosylate disulfate) 200 mg
† Daily Value not established.
iHerb Customer Reviews

very good to excellent product

Posted by iHerb Customer on January 26 2018 | Verified Purchase

as former war veteran (4 years of active war experience) more than 20 years, with registered PTSD diagnosis which developed to GAD, i have to say that this product works. i don`t know how but it works. i definitely didn't lose all my anxiety periods but i feel significantly better !!! i tried so many different official medicine but mostly i felt much side effects so i decided to avoid use of it. sam-e, 5 htp and gaba works, slowly but surely :) thanx

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Great product

Posted by iHerb Customer on January 10 2018 | Verified Purchase

Very effective and apart from mild headaches when first started taking it but within a day or two no ill effects

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Good price, good results

Posted by iHerb Customer on January 1 2018 | Verified Purchase

Good value for money, I wish it had a little less additives, but I feel so much better when using SAMe

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very good

Posted by iHerb Customer on December 7 2017 | Verified Purchase

very good sam-e thank you

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Excellent product

Posted by iHerb Customer on December 2 2017 | Verified Purchase

I am using Life Flo Health to prevent rampage at night. And it works very well.

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