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Now Foods, SAMe, 400 mg, 60 Tablets

$47.50 $47.50 (Saved $24.49)

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Now Foods, SAMe, 400 mg, 60 Tablets

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Now Foods, SAMe, 400 mg, 60 Tablets

In Stock
400 mg
400 mg
200 mg
  • Expiration Date: July 2019
  • Shipping Weight:
    0.84 lbs
    Switch to Metric units
  • Product Code: NOW-00141
  • UPC Code: 733739001412
  • Package Quantity: 60 Tablets
  • Dimensions:
    2.4 x 2.4 x 4.1 in, 0.5 lbs
    Switch to Metric units
Frequently Purchased Together
Product Overview


  • Nervous System Support
  • Supports Emotional Well-Being
  • Supports Joint Health
  • Enteric Coated
  • A Dietary Supplement
  • Vegetarian/Vegan
  • Amino Acids
  • Family Owned Since 1968
  • GMP Quality Assured

SAMe (S-adenosylmethionine), a compound native to the body, is a component of many biochemical reactions, including those that affect brain biochemistry and joint health. Numerous studies have indicated that SAMe can help to alleviate transient minor aches and pains resulting from overexertion or strain. In addition, because SAMe is also necessary for the synthesis of neurotransmitters, it plays an important role in mood support. NOW SAMe is enteric-coated, which makes it very well tolerated and protects it from degradation.

Suggested Use

Take 1 tablet 2 to 4 times daily, preferably on an empty stomach.

Other Ingredients

Cellulose, croscarmellose sodium, magnesium stearate (vegetable source), silica, stearic acid (vegetable source), ascorbic acid, citric acid and methacrylate, glycerin).

Not manufactured with wheat, gluten, soy, milk, egg, fish or shellfish ingredients. Produced in a GMP facility that processes other ingredients containing these allergens.


Do not eat freshness packet. Keep in bottle.

Natural color variation may occur in this product.

Refrigeration recommended after opening.

Caution: For adults only. Individuals with bipolar depression, anxiety disorders or taking antidepressant medications should not take SAMe unless under professional medical supervision. Consult physician if pregnant/nursing, taking medication, or have a medical condition. Keep out of reach of children.

Supplement Facts
Serving Size: 1 Tablet
  Amount Per Serving %Daily Value*
SAMe (S-Adenosyl-L-Methionine)
(from S-Adenosyl-L-Methionine Disulfate Tosylate)
400 mg *
* Daily Value not established.
iHerb Customer Reviews


Posted by iHerb Customer on April 29 2017 | Verified Purchase

works as well as any SAMe

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A real life saver

Posted by iHerb Customer on March 26 2017 | Verified Purchase

I had been ill for some years and although already on supplements, not making much progress toward getting better. I implored my doctor to find something else and he prescribed Sam-e. It turned my life around and I started getting noticeably better from that day.

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Good ingredients for SAM E

Posted by iHerb Customer on March 15 2017 | Verified Purchase

This product has good medicinal and fairly good non medicinal ingredients. A lot of SAM E's are yellow which is dye or has titanium dioxide etc in them which is not good. It does have magnesium stearate which they say isn't great either. So hard to find a perfect product of any kind!

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Posted by iHerb Customer on December 19 2016 | Verified Purchase

Good product great service

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Excellent Product

Posted by iHerb Customer on November 30 2016 | Verified Purchase

I won't live without this brand of SAM-e. Great for mood enhancement and reduction of joint pain.

Thanks for your feedback!