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NutraLife, The Original SAM-e (S-Adenosyl-L-Methionine), 400 mg, 30 Enteric Coated Tablets

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NutraLife, The Original SAM-e (S-Adenosyl-L-Methionine), 400 mg, 30 Enteric Coated Tablets

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NutraLife, The Original SAM-e (S-Adenosyl-L-Methionine), 400 mg, 30 Enteric Coated Tablets

In Stock
400 mg
200 mg
400 mg
30 Tablets
60 Tablets
30 Tablets
  • Expiration Date: Jul 2019
  • Shipping Weight:
    0.27 lbs
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  • Product Code: NLF-18009
  • UPC Code: 686149180096
  • Package Quantity: 30 Enteric Coated Tablets
  • Dimensions:
    6.2 x 3.4 x 1.8 in, 0.15 lbs
    Switch to Metric units
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Save $2.00 when you purchase these items today for only $23.37
Product Overview


  • New! Double Strength
  • 400 mg Active S-Adenosyl-Methionine Per Tablet
  • The Only Time-Proven Form of SAMe
  • Manufactured in Accordance with GMP
  • Dietary Supplement
  • NutraLife SAMe Enteric Coated Tablets are Kosher Certified by Star Kosher

Clinically Shown To Maintain:

  • Mood & Emotional Well Being
  • Healthy Liver Function
  • Joint Health and Comfort
  • Joint Mobility

SAMe is found in every living being. It is an important physiological agent synthesized by the body, and it is involved in over 40 biochemical reactions, some of which effect:

MOOD SAMe and Emotional Well Being:

SAMe is essential to the manufacture of many important brain compounds such as neurotransmitters and phospholipids, which are critical for maintaining healthy mood and emotional well-being.

JOINTS SAMe and Joint Mobility:

Clinical studies indicate that SAMe may play an important role in the manufacture of cartilage and that SAMe helps produce proteoglycans, essential components in healthy joint and mobility.

LIVER SAMe and Liver Function

SAMe is involved in many processes of the liver. SAMe is essential to maintaining glutathione levels, which is critical for proper liver function.

As people age, SAMe levels can decrease. SAMe supplementation may be an important factor in maintaining mobility, and a healthy body and mind.

NutraLife SAMe:

NutraLife SAMe is the same form that has been available in Europe for over two decades. NutraLife offers the only form of SAMe with 20 years of historical data for both effectiveness and safety. NutraLife SAMe is manufactured and packaged to ensure the highest quality and safety standards.

  • Each NutraLife SAMe tablet contains 400 mg of active S-Adenosyl-Methionine and is manufactured in full accordance with GMP.
  • NutraLife SAMe is the original SAMe brand introduced to the United States almost a decade ago.
  • NutraLife SAMe continues to be made with the highest quality active S,S isomer SAMe raw material.
  • NutraLife SAMe is kosher certified by Star-K and contains NO animal byproducts.
  • NutraLife SAMe does not contain Talc.
  • NutraLife SAMe tablets are manufactured in a carefully controlled environment and are cold form blister packed to ensure a more than two year stability rating.

Please consult package insert for more information on NutraLife SAMe.

Suggested Use

Clinical studies show that supplementation of 400 mg (or one tablet) a day is effective for most people. Different levels of supplementation may be beneficial to some people. Please refer to our package insert for more information.

Other Ingredients

S-Adenosyl-Methionine tosylate disulfate, cellulose, mannitol, citric acid, stearic acid, silica, sodium starch glycolate, modified cellulose gum.

Coating Ingredients: Hydroxypropyl methylcellulose phthalate or methacrylic acid copolymer and hydroxypropyl methylcellulose; triacetin, titanium dioxide, yellow ochre.

This product contains no peanuts, eggs, dairy, soy, wheat, yeast, gluten, tree nuts, crustacean shellfish, fish or other animal byproducts.

Each NutraLife SAMe tablet contains 800 mg SAMe tosylate disulfate, which includes 400 mg of the active ingredient SAMe (S-Adenosyl-Methionine).


NutraLife SAMe tablets are sealed in blister packs to ensure product safety, quality and freshness.

This product should be stored in a cool, dry place.


Do not use if blister foil is punctured or appears in any way to have been tampered with. Keep out of reach of children. If you are currently taking prescription anti-depressants, consult your physician before using SAMe. If you suffer from bipolar (manic) depression, do not use this product. If you are pregnant or lactating, consult your physician before taking this product.

Supplement Facts
Serving Size: 1 Tablet
Servings Per Container: 30
  Amount Per Serving %DV
S-Adenosyl-Methionine 400 mg *
*Daily Value not established
iHerb Customer Reviews

The only one that appears not to contain magnesium stearate

Posted by iHerb Customer on Sep 09, 2017 | Verified Purchase

I hit a wall of grief after the death of a family member, and needed some help to lift me out (I absolutely will not take prescription anti-depressants! I'm a psychotherapist and have done my research well). This really seemed to help, especially after about 2 weeks - and it's good to know it's helping my liver and joints too. I'll drop down to 200mg soon., but then I might keep taking it, as I haven't noticed any side effects and I like the benefits.

Thanks for your feedback!

SAMe 400

Posted by iHerb Customer on Jul 22, 2017 | Verified Purchase

I love this brand of SAMe and I especially love the price. Helps a lot with my arthritis in my spine and it really does improve mood.

Thanks for your feedback!


Posted by iHerb Customer on Jul 02, 2017 | Verified Purchase

Really good for the liver, and also I feel like it is working for back/neck pain also. I like this brand because of the ingredients and the price it right. I took 200mg for a long time, but I only noticed the results after taking 800-1200mg for two weeks, and then a maintenance of 400mg per day.

Thanks for your feedback!

Seems ok so far

Posted by BlueMountaineer on Jun 26, 2017 | Verified Purchase

Started using this brand instead of Drs Best as they were a bit cheaper. The ingredients were slightly different and I'm not entirely confident in them, however I'm cutting down from 2 to 1 per day as my mood has been very good for a while now. SAMe was a life-saver for me for several years and I could not manage without it, but I think must be finally improving enough to cut down. I will update when I have used this brand more.

Thanks for your feedback!

SAMe-so beneficial

Posted by iHerb Customer on May 07, 2017 | Verified Purchase

I've been taking SAM-e for years. It has so many benefits (immune system, mood, etc.). It has been used in Europe for over 50 years where they have done a lot of reaearch on it. Nutralife was the first on the market here and is the best price. I take 400Mg. every morning. Wouldn't be without it.

Thanks for your feedback!