Your Cart is Empty
But it doesn't have to be.
Continue Shopping.
Added to Cart
Cart Total:
Customers Also Bought:

Thorne Research, Indole-3-Carbinol, 60 Veggie Caps

Thorne Research, Indole-3-Carbinol, 60 Veggie Caps

Earn 5% Loyalty Credit ?
Our Price:
Shipping Saver ?
You Save:
$0.01 (0)

Sorry, this product is no longer in stock.

In Stock
  • Expiration Date: Dec 2018
  • Shipping Weight:
    0.12 lbs
    Switch to Metric units
  • Product Code: THR-74903
  • UPC Code: 693749749035
  • Package Quantity: 60 Veggie Caps
  • Dimensions:
    3.8 x 2 x 2 in, 0.1 lbs
    Switch to Metric units
  • The bottles of this item may have some dis-colorization due to oxidation. However, we have been re-assured by the manufacturer that this does NOT affect the product itself by anyway. - iHerb

Bundle Offer
Save $4.00 when you purchase these items today for only $31.60
Total: $35.60
Combo Discount: - $4.00
Together: $31.60

Sorry, this product is no longer in stock.

Product Overview


  • Dietary Supplement
  • Hypoallergenic
  • To Support Estrogen Metabolism
  • Maintains Optimal 2-Hydroxy/16-Hydroxy Estrogen Ratios
  • Found in Cabbage Family Vegetables, it's a Source of DIM
  • Nutritional Support for Liver Detoxification
  • Made Without Flowing Agents that can Inhibit Bioavailability

Indole-3-carbinol (I3C) is a compound found in high concentrations in vegetables of the Brassica family, including broccoli, cauliflower, Brussels sprouts, and cabbage.

As a dietary supplement, I3C provides key nutritional support for liver detoxification. It also plays an important role in supporting female reproductive health. The majority of ingested I3C is absorbed in the small intestine as diindolylmethane (DIM), which is thought to be the primary contributor to I3C's beneficial properties. DIM has been shown to selectively bind to estrogen receptors and may act as an estrogen antagonist at physiological concentration.

In the liver, I3C promotes the metabolism of estrogen and increases the ratio of 2-hydroxy estrogen to 16-hydroxy estrogen. The 2-hydroxy estrogens, less active than the 16-hydroxy estrogens, generally are eliminated more rapidly from the body. One prospective study found postmenopausal women with the most favorable urinary 2:16-hydroxyestrone ratio were most likely to maintain good female health.

Preliminary studies have examined the efficacy, safety, and optimal supplementation of I3C. A 12-week phase I trial conducted on 17 women found a 66-percent increase in urinary 2:16-hydroxyestrone ratio with administration of 400 mg I3C daily.

Suggested Use

Take 1 capsule one to two times daily or as recommended by your health-care practitioner.

Other Ingredients

Hypromellose (derived from cellulose) capsule, microcrystalline cellulose, leucine, silicon dioxide.


Tamper Evident: Use only if bottle is sealed.

If pregnant, consult your health-care practitioner before using this product.

Store tightly sealed in a cool, dry place.

Supplement Facts
Serving Size: One Capsule
  Amount Per Serving % DV
Indole 3-carbinol / Diindolylmethane (DIM) complex 200 mg *
* Daily Value (DV) not established.
iHerb Customer Reviews

good for my health problem

Posted by Reviewer2083236 on Apr 23, 2017 | Verified Purchase

I was told to take this for an ongoing health problem by a nutritionist at Mayo. Works for me.

Was this review helpful to you?

Thanks for your feedback!


Posted by 5206497610015347026 on Apr 22, 2017 | Verified Purchase

Not sure whether this product works or not, my trainer has me taking them and as i'm on a controlled diet and exercise plan I'll never know which one works 😂😂

Was this review helpful to you?

Thanks for your feedback!

Great product

Posted by 4926784846766521077 on Mar 02, 2017 | Verified Purchase

This Indol-3-Carbinol is the best on the market that I've found. I've tried quite a few & the Thorne Research works the best. Highly recommend this product

Was this review helpful to you?

Thanks for your feedback!

Great, hard to find product!

Posted by 5359585282423800257 on Dec 01, 2016 | Verified Purchase

Love this supplement! Great for the immune system!

Was this review helpful to you?

Thanks for your feedback!

Great product with no fillers

Posted by 5314027903119101750 on Mar 21, 2016 | Verified Purchase

This is the purest I-3-C currently available on i-Herb and represents great value for money

Was this review helpful to you?

Thanks for your feedback!