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Thorne Research, Methyl-Guard Plus, 90 Veggie Caps

Thorne Research, Methyl-Guard Plus, 90 Veggie Caps

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In Stock
  • Expiration Date: Feb 2019
  • Shipping Weight:
    0.3 lbs
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  • Product Code: THR-78901
  • UPC Code: 693749789017
  • Package Quantity: 90 Veggie Caps
  • Dimensions:
    4.4 x 2.4 x 2.4 in, 0.25 lbs
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Bundle Offer
Save $2.00 when you purchase these items today for only $53.35
Total: $55.35
Combo Discount: - $2.00
Together: $53.35

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Product Overview


  • Dietary Supplement
  • Hypoallergenic
  • More Concentrated Methylation Support
  • Contains Higher Amounts of 5MTHF (Active Folate), B6, B12
  • Riboflavin 5'-Phosphate Added for Extra Homocysteine Metabolism Support
  • Easy 3 Capsules Daily Dosing

Methylation – the addition of a methyl group (CH4 – one carbon attached to three hydrogens) to another molecule – is an essential and vital biochemical process within the human body that is involved in a large number of biochemical pathways involving neurotransmitters, detoxification, cardiovascular health, eye health, muscle health, bone health, and redox balance. A number of specific nutrients are necessary for methylation to occur normally.

Methyl-Guard Plus contains higher amounts of 5MTHF (the active form of folate), pyridoxal 5'-phosphate (active B6), and methylcobalamin (active B12), than our original Methyl-Guard. We have also added riboflavin 5'-phosphate (the active form of vitamin B2) for its positive effect on homocysteine metabolism and methylation. These ingredients provide the necessary nutrients the body uses to push forward the process of methylation. Methyl-Guard Plus is more concentrated, so your patients will appreciate the recommended daily amount of three capsules, which will improve compliance. Our original Methyl-Guard is still available.

Suggested Use

Take 1-3 capsules daily or as recommended by a health-care practitioner.

Other Ingredients

Hypromellose (derived from cellulose) capsule, calcium citrate, calcium laurate.


Tamper evident: Use only if bottle is sealed.

If pregnant, consult your health-care practitioner before using this product.

Store tightly sealed in a cool, dry place.

Supplement Facts
Serving Size: Three Capsules
Servings Per Container: 30
Three Capsules Contain: Amount Per Serving %Daily Value
Riboflavin (as Riboflavin 5'-Phosphate Sodium) 90 mg 5,295%
Vitamin B6 (as Pyridoxal 5'-Phosphate) 45 mg 2,250%
Folate (as L-5-Methyltetrahydrofolate from L-5-Methyltetrahydrofolic Acid, Glucosamine Salt) 3 mg 750%
Vitamin B12 (as Methylcobalamin) 3 mg 50,000%
Betaine Anhydrous (Trimethylglycine) 1.8 g *
*Daily Value (DV) not established.
iHerb Customer Reviews

pricey however has all the GOOD vitamin Bs that you need - MTHFR must

Posted by 5224430532336233514 on Jun 06, 2017 | Verified Purchase

Lowers homocysteine and has all the right vitamins B, recommend it - i just wish it wasn't so pricey

Thanks for your feedback!

Bardzo dobry

Posted by 4816851269470813899 on May 30, 2017 | Verified Purchase

Bardzo dobry produkt.

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A must for MTHFR

Posted by 5636006862556358334 on May 22, 2017 | Verified Purchase

Absolutely essential for me with the MTHFR homozygous gene mutation. It takes time to build up the correct dose and can make you queasy at first, but when it starts working, or should I say, when you body works enough to accept it, it is life changing. This brand is easy to get in Australia therefore I wouldn't use another brand, although have tried others from USA without trouble.

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Posted by 4817553915394586435 on Apr 19, 2017 | Verified Purchase

I recently discovered that I have an MTHFR mutation and that I have a long standing folate and B12 deficiency, which have been causing me a lot of health issues. I recently started with regular methylcobalamin injections, along with these. I love this stuff. It has everything that you need if you suffer from this genetic mutation. I think that I am even noticing an improvement in my grey hair. It has certainly helped with depression, and anxiety.

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Good Product.

Posted by 5182866630898517178 on Apr 17, 2017 | Verified Purchase

My dr recommended these as I have a double mutation of the MTHFR gene. I need to make sure I have them after food as I can feel nauseous but apart from that they have been fine.

Thanks for your feedback!