I am on my fourth day of using this product and so far, so good. You take the capsules/tablets in the evening, so there is a little bit of stomach action going on when you go to bed, but by morning, you dump the waste and you are good to go the next day- no discomfort during the day. I feel like I am really clean on the inside- not stuffy and pretty energetic. Have not had any diarrhea, although generally do try to eat mostly whole unprocessed foods with lots of fruits and vegetables. My husband is interested in trying this, so will probably repeat this every couple of months.