I've tried many Urinary Support formulas from many different manufacturers for my recurring UTIs. This one is the best by far. It contains herbs that are effective against both Gram + and Gram - bacteria, whereas most other brands are only effective against one or the other. Since being on this supplement (I take 2 capsules a day plus one D-mannose capsule, about an hour before breakfast) I have had NO UTIs at all. I could not say that about D-mannose alone or any other supplement. VERY pleased with this, and will continue to reorder. Thanks.