I have (had) an impaired liver & have tried many, many things over the years to keep it healthy. This has helped to lower my ALT & AST levels along with Thorne Research T.A.P.S. formula (also excellent for the liver), Jarrow or Thorne Research Milk thistle, Paradise Reishi, Kroeger Herb or Paradise Schizandra, & Seven Forests Salvia-Ligustrum tablets. I also take a high quality multi-vitamin (Thorne Research Basic Nutrients WITHOUT copper & iron), drink dandelion tea frequently, & consume extra vitamin C. The above protocol has been the magic bullet in lowering my liver enzymes ( lab results confirmed) . I usually rotate the Liver Optimizer with Thorne Research T.A.P.S. and the Salvia Ligustrum. The herbs I take most every day are schizandra and milk thistle. Schizandra is by far one my favorite herbs of all time, as it has a very positive effect on the liver, mind and skin. For those who are sick, I'd suggest taking ALL of the supplements, if possible, together (double the schizandra!) until the enzymes and/or viral load come down. I was quite sick until I learned of the above supplements. It should be noted that I am absolutely not a doctor. This is just what happens to work for me.