I've recently tried/reverted to a couple of TwinLab products after trying other brands and realising TwinLab use much less filler - their caps are usually VERY small, which I like. Small caps mean less filler and that means less toxic junk. However - I found this dose simply too much in one cap, and because the caps are very small, they're too hard to pull apart in order to take less. I guess you could say this is very effective (or toxic), because I found it to cause an extremely nasty/flat/lethargic/heavy gravity feeling that rendered me unable to move/sliding down my chair/needing to stay horizontal plus nausea that didn't - start - to go away until I took some iodine and zinc to compensate and the iodine/zinc started to metabolise. It was awful - I felt like rubbish for a good few hours. Note that I take iodine every day and zinc pretty much every day, so it's unlikely I'm deficient. I've successfully been taking 50mcg of a different selenium product and this has never happened before, nor did it happen with a liquid selenate I've tried in the past. The thyroid needs selenium to convert thyroid hormone T4 to T3; selenium and zinc are antagonists (which I knew - as are selenium/magnesium) - so either this is a terrible product that simply doesn't agree with me, or I need much less selenium than 250mcg. Most frustrating - I was really looking forward to trying this because it's the same type that's been used in asthma/inflammation/circadian rhythm studies. I wish TwinLab did a 50 or 100mcg cap - I personally feel that would be ideal, because it'd mean other nutrients don't need to be increased/megadosed to compensate. I just don't understand the megadosing thing within the supplement industry - a lot is seldom better. At this point, I'm highly unlikely to take this one ever again - the reaction was that bad that I won't risk it. I'll stick to food and/or cutting a 100mcg tab in half. Suggestion - if you have a health issue that relies on iodine, zinc, magnesium or phosphorus supplementation or struggle with low levels of any of these nutrients - perhaps avoid this selenium at this dose, or open the caps and try taking less initially. If this review was helpful to you, please click YES below - thank you. For reviews of all the products I have purchased from iHerb, please click my username above.
