Customer Reviews

Sixty percent of people are either heterozygous or homozygous for the MTHFR polymorphism, meaning regular folic acid is not only useless, but potentially harmful because it blocks absorption of the meagre amounts of methyl folate we receive. Methyl folate, as the activated form, completely bypasses this problem. Methyl folate is so important for methylation pathways, and a lack can contribute to depression, elevated homocysteine levels, CFS/ME, fibromyalgia, heart disease, fertility problems, and a host of other degenerative conditions. This product is so important, particularly since most supplements are full of folic acid which as I said above can cause more harm than good. Everyone should be taking this instead. Highly, highly recommended. Thanks for stocking it iHerb!!!

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A fine product to ward off headaches, malnutrition, and mild depression. Especially effective against high homocysteine levels when combined with TMG and a good all-around B complex vitamin formula.

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L-methylfolate - the active form of folate in the blood and the only type that can cross the blood-brain barrier. Unlike regular folic acid, Metafolin does not require enzymatic conversion to L-methylfolate in the body. By providing L-methylfolate directly, this patented form of folic acid may have benefits for those who do not produce enough L-methylfolate in response to folic acid supplementation. For those who take proper doses of vitamins B12 and B6, and TMG (trimethylglycine), but still suffer from higher-than-optimal homocysteine, Metafolin may be the solution. - - - - - - - - - - - - - - - - The only one problem with this item is that Solgar company uses so many ingredients(magnesium stearate, mannitol, stearic acid) which hinder the absorption of active ingredient.

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You can melt tablets in your mouth. Sweet taste. Same as prescription food.

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My husband drags unless he takes B vitamins daily, and even that is sometimes not enough. I read that adding a large dose of folate helps the other B vitamins be more reactive. I don't know if this is true or not, but thought I may as well try it. My husband says it has made a huge difference in his energy level. Thanks for this product!

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